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Titolo:
Evaluation of the role for prolactin-releasing peptide in prolactin secretion induced by ether stress and suckling in the rat: comparison with vasoactive intestinal peptide
Autore:
Watanobe, H; Schioth, HB; Wikberg, JES; Suda, T;
Indirizzi:
Hirosaki Univ, Sch Med, Dept Internal Med 3, Hirosaki, Aomori 0368562, Japan Hirosaki Univ Hirosaki Aomori Japan 0368562 rosaki, Aomori 0368562, Japan Uppsala Univ, Dept Pharmaceut Pharmacol, SE-75124 Uppsala, Sweden Uppsala Univ Uppsala Sweden SE-75124 Pharmacol, SE-75124 Uppsala, Sweden Melacure Therapeut, Uppsala, Sweden Melacure Therapeut Uppsala SwedenMelacure Therapeut, Uppsala, Sweden
Titolo Testata:
BRAIN RESEARCH
fascicolo: 1, volume: 865, anno: 2000,
pagine: 91 - 96
SICI:
0006-8993(20000519)865:1<91:EOTRFP>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTERIOR-PITUITARY; LUTEINIZING-HORMONE; NEONATAL ANDROGENIZATION; FEMALE RATS; POLYPEPTIDE; BRAIN; HYPOTHALAMUS; RECEPTOR; TISSUE; SURGES;
Keywords:
prolactin; prolactin-releasing peptide; vasoactive intestinal peptide; ether stress; suckling;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Watanobe, H Hirosaki Univ, Sch Med, Dept Internal Med 3, 5 Zaifu Cho, Hirosaki, Aomori0368562, Japan Hirosaki Univ 5 Zaifu Cho Hirosaki Aomori Japan 0368562 Japan
Citazione:
H. Watanobe et al., "Evaluation of the role for prolactin-releasing peptide in prolactin secretion induced by ether stress and suckling in the rat: comparison with vasoactive intestinal peptide", BRAIN RES, 865(1), 2000, pp. 91-96

Abstract

Prolactin (PRL)-releasing peptide (PrRP) is a recently discovered hypothalamic peptide possessing a specific stimulatory action on PRL secretion. In this study, we examined whether PrRP plays a role in mediating ether stress- and suckling-induced PRL secretion in rats through administering anti-PrRP antisera intracerebroventricularly. For comparison, we also tested the effect of anti-vasoactive intestinal peptide (VIP) antisera on the hormonal responses, since VIP is another candidate for a physiological PRL-releasing factor. The immunoneutralization of VIP, but not of PrRP, led to a significant suppression of PRL responses to both ether and suckling. These results suggest that PrRP may not play a significant role, or at least play a much weaker role than VIP, in mediating PRL release induced by ether stress and suckling in the rat. (C) 2000 Elsevier Science B.V All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 05:03:14