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Titolo:
Renal involvement in primary Sjogren's syndrome
Autore:
Aasarod, K; Haga, HJ; Berg, KJ; Hammerstrom, J; Jorstad, S;
Indirizzi:
Univ Trondheim Hosp, Dept Med, N-7006 Trondheim, Norway Univ Trondheim Hosp Trondheim Norway N-7006 ed, N-7006 Trondheim, Norway Haukeland Univ Hosp, Ctr Rheumatol, N-5021 Bergen, Norway Haukeland Univ Hosp Bergen Norway N-5021 heumatol, N-5021 Bergen, Norway Natl Hosp, Lab Renal Physiol, Oslo, Norway Natl Hosp Oslo NorwayNatl Hosp, Lab Renal Physiol, Oslo, Norway
Titolo Testata:
QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS
fascicolo: 5, volume: 93, anno: 2000,
pagine: 297 - 304
SICI:
1460-2725(200005)93:5<297:RIIPSS>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOW URINARY CITRATE; DISEASE; NEPHROLITHIASIS; HISTOPATHOLOGY; BIOPSIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Aasarod, K Univ Trondheim Hosp, Dept Med, Olav Kyrres Gate 17, N-7006 Trondheim, Norway Univ Trondheim Hosp Olav Kyrres Gate 17 Trondheim Norway N-7006
Citazione:
K. Aasarod et al., "Renal involvement in primary Sjogren's syndrome", QJM-MON J A, 93(5), 2000, pp. 297-304

Abstract

Renal involvement was evaluated in 62 patients with primary Sjogren's syndrome, classified according to criteria proposed by The European Classification Criteria Group. Urine concentration capacity was tested using intranasal 1-desamino-8-D-arginine-vasopressin. For patients with urine pH >5.5 without metabolic acidosis (n = 28), an acidification test with ammonium chloride was performed. Urinary citrate, albumin, NAG, ALP and beta 2-microglobulin were measured and creatinine clearance was calculated. Maximum urine concentration capacity and creatinine clearance were reduced in 13 (21%). Albumin excretion was >30 mu g/min in only one patient (1.6%). Seven patients (11.3%) had complete or incomplete distal renal tubular acidosis (dRTA), four had reduced creatinine clearance and five had reduced maximum urine concentration capacity. The ratio of citrate/creatinine in spot urine was below the 2.5 percentile in all patients with complete or incomplete dRTA. The prevalence of dRTA was lower than in previous studies, There were also few patients with signs of glomerular disease (1.6%). The use of citrate:creatinine ratio in spot urine can be a helpful method in identifying patients withcomplete or incomplete dRTA.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 15:29:27