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Titolo:
Molecular genetics of migraine headaches: a review
Autore:
Montagna, P;
Indirizzi:
Univ Bologna, Sch Med, Inst Clin Neurol, I-40123 Bologna, Italy Univ Bologna Bologna Italy I-40123 t Clin Neurol, I-40123 Bologna, Italy
Titolo Testata:
CEPHALALGIA
fascicolo: 1, volume: 20, anno: 2000,
pagine: 3 - 14
SICI:
0333-1024(200002)20:1<3:MGOMHA>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
FAMILIAL HEMIPLEGIC MIGRAINE; CALCIUM-CHANNEL GENE; AUTOSOMAL-DOMINANT ARTERIOPATHY; SPINOCEREBELLAR ATAXIA TYPE-6; MITOCHONDRIAL-DNA MUTATIONS; DRD2 NCOI ALLELES; FACTOR-V-LEIDEN; SEGREGATION ANALYSIS; CLUSTER HEADACHE; EPISODIC ATAXIA;
Keywords:
migraine; genetics; calcium channels; familial hemiplegic migraine;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
104
Recensione:
Indirizzi per estratti:
Indirizzo: Montagna, P Univ Bologna, Sch Med, Inst Clin Neurol, Via Ugo Foscolo 7, I-40123 Bologna, Italy Univ Bologna Via Ugo Foscolo 7 Bologna Italy I-40123 a, Italy
Citazione:
P. Montagna, "Molecular genetics of migraine headaches: a review", CEPHALALGIA, 20(1), 2000, pp. 3-14

Abstract

Following the recent discovery of neural calcium channel mutations in familial hemiplegic migraine, genetic linkage and association studies have beenperformed world-wide in an effort to unveil the genetic basis of the more common types of migraine too. Mutations in neural calcium channels, mitochondrial DNA, serotonin receptors and transporter, dopamine receptors and genetic prothrombotic risk factors have been especially investigated and are discussed here. No unambiguous conclusions have, however, been reached. FHM remains an isolated success story in the quest for the genetic basis of migraine.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 10:13:13