Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Further evidence for a central reorganisation of synaptic connectivity in patients with hypoglossal-facial anastomosis in man
Autore:
Tankere, F; Maisonobe, T; Naccache, L; Lamas, G; Soudant, J; Danziger, N; Bouche, P; Fournier, E; Willer, JC;
Indirizzi:
Hop La Pitie Salpetriere, Federat Clin Neurophysiol, F-75013 Paris, FranceHop La Pitie Salpetriere Paris France F-75013 iol, F-75013 Paris, France Hop La Pitie Salpetriere, Dept ENT, F-75013 Paris, France Hop La Pitie Salpetriere Paris France F-75013 ENT, F-75013 Paris, France
Titolo Testata:
BRAIN RESEARCH
fascicolo: 1, volume: 864, anno: 2000,
pagine: 87 - 94
SICI:
0006-8993(20000502)864:1<87:FEFACR>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ELECTROPHYSIOLOGICAL EVIDENCE; NERVE ANASTOMOSIS; MUSCLE AFFERENTS; BLINK REFLEX; ORGANIZATION; MOTONEURONS; NUCLEUS; CAT; SYNAPSES; RAT;
Keywords:
trigemino-hypoglossal-facial reflexes; cutaneous and mucosal afferents; hypoglossal-facial anastomosis; synaptic plasticity; man;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Willer, JC Hop La Pitie Salpetriere, Federat Clin Neurophysiol, F-75013 Paris, France Hop La Pitie Salpetriere Paris France F-75013 3 Paris, France
Citazione:
F. Tankere et al., "Further evidence for a central reorganisation of synaptic connectivity in patients with hypoglossal-facial anastomosis in man", BRAIN RES, 864(1), 2000, pp. 87-94

Abstract

In normal subjects, electrical stimulation of trigeminal mucosal afferents(lingual nerve - V3) can elicit a short latency (12.5+/-0.3 ms; mean+/-S.D.) reflex response in the ipsilateral genioglossus muscle (Maisonobe et al., Reflexes elicited from cutaneous and mucosal trigeminal afferents in normal human subjects. Brain Res. 1998;810:220-228). In the present study on patients with hypoglossal-facial (XII-VII) nerve anastomoses, we were able torecord similar R1-type blink reflex responses in the orbicularis oculi muscles, following stimulation of either supraorbital nerve (V1) or lingual nerve (V3) afferents. However, these responses were not present in normal control subjects. Voluntary swallowing movements produced clear-cut facilitations of the R1 blink reflex response elicited by stimulation of VI afferents. In a conditioning-test procedure with a variable inter-stimulus interval,the R1 blink reflex response elicited by supraorbital nerve stimulation was facilitated by an ipsilateral mucosal conditioning stimulus in the V3 region. This facilitatory effect was maximal when the two stimuli (conditioning and test) were applied simultaneously. This effect was not observed on the R1 component of the blink reflex in the normal control subjects. These data strongly suggest that in patients with XII-VII anastomoses, but not in normal subjects, both cutaneous (VI) and mucosal (V3) trigeminal afferents project onto the same interneurones in the trigeminal principal sensory nucleus. This clearly supports the idea that peripheral manipulation of the VIIth and the XIIth nerves induces a plastic change within this nucleus. (C) 2000 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/07/20 alle ore 07:44:12