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Titolo:
Developing chicken oligodendrocytes express the type IV oligodendrocyte marker T4-O in situ, but not in vitro
Autore:
Anderson, ES; Bjartmar, C; Eriksson, C; Westermark, G; Hildebrand, C;
Indirizzi:
Linkoping Univ, Fac Hlth Sci, Div Cell Biol, Dept Biomed & Surg, SE-58185 Linkoping, Sweden Linkoping Univ Linkoping Sweden SE-58185 urg, SE-58185 Linkoping, Sweden
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 1-2, volume: 284, anno: 2000,
pagine: 21 - 24
SICI:
0304-3940(20000421)284:1-2<21:DCOETT>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTERIOR MEDULLARY VELUM; CELL-SHAPE; RAT; HETEROGENEITY; UNIT;
Keywords:
chicken; oligodendrocyte; spinal cord; white matter; development; myelination; T4-O; cell culture;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Anderson, ES Linkoping Univ, Fac Hlth Sci, Div Cell Biol, Dept Biomed & Surg, SE-58185 Linkoping, Sweden Linkoping Univ Linkoping Sweden SE-58185 Linkoping, Sweden
Citazione:
E.S. Anderson et al., "Developing chicken oligodendrocytes express the type IV oligodendrocyte marker T4-O in situ, but not in vitro", NEUROSCI L, 284(1-2), 2000, pp. 21-24

Abstract

Accumulating data suggest that the oligodendrocyte population includes morphological and biochemical subtypes. We recently reported that a polyclonalantiserum against an unknown antigen, the T4-O molecule, labels a subpopulation of chicken oligodendrocytes, obviously representing the type IV variety of Del Rio Hortega. The present study examines the developmental expression of the T4-O molecule in situ and in vitro. The results show that T4-O immunoreactive cells first appear at E15 in the ventral funiculus. But, oligodendrocytes cultured in vitro with or without neurones do not develop a T4-O immunoreactivity. We conclude that oligodendrocytes in the spinal cord of chicken embryos first express the T4-O molecule some time after onset of myelination, and that the T4-O immunoreactive phenotype does not develop invitro. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/21 alle ore 03:44:11