Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Brain MRI lesions and atrophy are related to depression in multiple sclerosis
Autore:
Bakshi, R; Czarnecki, D; Shaikh, ZA; Priore, RL; Janardhan, V; Kaliszly, Z; Kinkel, PR;
Indirizzi:
SUNY Buffalo, Sch Med & Biomed Sci, Buffalo Gen Hosp, Dept Imaging Serv, Buffalo, NY 14203 USA SUNY Buffalo Buffalo NY USA 14203 ept Imaging Serv, Buffalo, NY 14203 USA SUNY Buffalo, Sch Med & Biomed Sci, Buffalo Gen Hosp, Dept Neurol E2, Buffalo, NY 14203 USA SUNY Buffalo Buffalo NY USA 14203 , Dept Neurol E2, Buffalo, NY 14203 USA SUNY Buffalo, Sch Med & Biomed Sci, Buffalo Gen Hosp, Dept Internal Med, Buffalo, NY 14203 USA SUNY Buffalo Buffalo NY USA 14203 ept Internal Med, Buffalo, NY 14203 USA SUNY Buffalo, Sch Med & Biomed Sci, Buffalo Gen Hosp, Dept Rehabil Med, Buffalo, NY 14203 USA SUNY Buffalo Buffalo NY USA 14203 Dept Rehabil Med, Buffalo, NY 14203 USA SUNY Buffalo, Sch Med & Biomed Sci, Buffalo Gen Hosp, Dept Social & Prevent Med,Div Biostat, Buffalo, NY 14203 USA SUNY Buffalo Buffalo NY USA 14203 Med,Div Biostat, Buffalo, NY 14203 USA SUNY Buffalo, Sch Med & Biomed Sci, Buffalo Gen Hosp, Lucy Dent Imaging Ctr, Buffalo, NY 14203 USA SUNY Buffalo Buffalo NY USA 14203 Dent Imaging Ctr, Buffalo, NY 14203 USA SUNY Buffalo, Sch Med & Biomed Sci, Buffalo Gen Hosp, Dent Neurol Inst, Buffalo, NY 14203 USA SUNY Buffalo Buffalo NY USA 14203 Dent Neurol Inst, Buffalo, NY 14203 USA Kaleida Hlth, Buffalo, NY 14203 USA Kaleida Hlth Buffalo NY USA 14203Kaleida Hlth, Buffalo, NY 14203 USA
Titolo Testata:
NEUROREPORT
fascicolo: 6, volume: 11, anno: 2000,
pagine: 1153 - 1158
SICI:
0959-4965(20000427)11:6<1153:BMLAAA>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
EMISSION-TOMOGRAPHY; UNIPOLAR DEPRESSION; MOOD DISORDERS; HYPOMETABOLISM; ABNORMALITIES; INVOLVEMENT; DISEASE; LOBE;
Keywords:
brain atrophy; demyelination; depression; MRI; multiple sclerosis; white matter disease;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Bakshi, R SUNY Buffalo, Sch Med & Biomed Sci, Buffalo Gen Hosp, Dept Imaging Serv, 100 High St, Buffalo, NY 14203 USA SUNY Buffalo 100 High St Buffalo NY USA 14203 falo, NY 14203 USA
Citazione:
R. Bakshi et al., "Brain MRI lesions and atrophy are related to depression in multiple sclerosis", NEUROREPORT, 11(6), 2000, pp. 1153-1158

Abstract

It is unclear whether brain MRI lesions are associated with depression in multiple sclerosis (MS). Neurological dysfunction in depressed (n = 19) andnon-depressed (n = 29) MS patients was rated by expanded disability statusscale (EDSS). EDSS was weakly predictive of the presence of (P = 0.03) andseverity of (p = 0.01) depression. After correcting for EDSS, the presenceof depression was predicted by superior frontal and superior parietal hypointense T1 lesions (p< 0.01); the severity of depression was predicted by superior frontal, superior parietal and temporal T1 lesions, lateral and third ventricular enlargement, and frontal atrophy (p < 0.01). Depression was not related to bright T2 lesions or enhancement. We conclude that atrophy and cortical-subcortical disconnection due to frontal and parietal white matter destructive lesions may contribute to depression in MS. NeuroReport 11:1153-1158 (C) 2000 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 02:14:35