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Titolo:
Occupational exposure to methyl isobutyl ketone causes lasting impairment in working memory
Autore:
Grober, E; Schaumburg, HH;
Indirizzi:
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10461 USA Albert EinsteinColl Med Bronx NY USA 10461 t Neurol, Bronx, NY 10461 USA Montefiore Med Ctr, Bronx, NY 10467 USA Montefiore Med Ctr Bronx NY USA 10467 efiore Med Ctr, Bronx, NY 10467 USA
Titolo Testata:
NEUROLOGY
fascicolo: 9, volume: 54, anno: 2000,
pagine: 1853 - 1855
SICI:
0028-3878(20000509)54:9<1853:OETMIK>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
ETHYL KETONE;
Keywords:
methyl isobutyl ketone; working memory; cognitive dysfunction; occupational exposure;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
7
Recensione:
Indirizzi per estratti:
Indirizzo: Schaumburg, HH Albert Einstein Coll Med, Dept Neurol, 1300 Morris Pk Ave, Bronx, NY 10461USA Albert Einstein Coll Med 1300 Morris Pk Ave Bronx NY USA10461
Citazione:
E. Grober e H.H. Schaumburg, "Occupational exposure to methyl isobutyl ketone causes lasting impairment in working memory", NEUROLOGY, 54(9), 2000, pp. 1853-1855

Abstract

The authors describe serial evaluations of a 44-year-old man who became cognitively impaired during a 6-year period of repeated exposure to high levels of methyl isobutyl ketone (MIBK). Neuropsychological tests administered six times over 10 years demonstrated a stable pattern of cognitive impairment. Dynamic imaging studies suggested persistent CNS dysfunction. The authors conclude that chronic, high-level, occupational MIBK exposure can cause a persistent cognitive syndrome best explained by impaired working memory.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 09:10:07