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Titolo:
In vitro fertilization outcomes after intracytoplasmic sperm injection with fresh or frozen-thawed testicular spermatozoa
Autore:
Habermann, H; Seo, R; Cieslak, J; Niederberger, C; Prins, GS; Ross, L;
Indirizzi:
Univ Illinois, Dept Urol, Chicago, IL 60612 USA Univ Illinois Chicago IL USA 60612 nois, Dept Urol, Chicago, IL 60612 USA Illinois Masonic Med Ctr, Inst Reprod Genet, Chicago, IL 60657 USA Illinois Masonic Med Ctr Chicago IL USA 60657 enet, Chicago, IL 60657 USA
Titolo Testata:
FERTILITY AND STERILITY
fascicolo: 5, volume: 73, anno: 2000,
pagine: 955 - 960
SICI:
0015-0282(200005)73:5<955:IVFOAI>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENETIC TIME BOMB; NONOBSTRUCTIVE AZOOSPERMIA; PREGNANCIES; EXTRACTION; QUALITY; BIOPSY; DEBATE; ICSI; MEN;
Keywords:
testis; sperm; cryopreservation; in vitro fertilization; intracytoplasmic sperm injection; testicular sperm extraction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Prins, GS Univ Illinois, Dept Urol, M-C 955, Chicago, IL 60612 USA Univ Illinois M-C 955 Chicago IL USA 60612 Chicago, IL 60612 USA
Citazione:
H. Habermann et al., "In vitro fertilization outcomes after intracytoplasmic sperm injection with fresh or frozen-thawed testicular spermatozoa", FERT STERIL, 73(5), 2000, pp. 955-960

Abstract

Objective: To compare the outcomes of intracytoplasmic sperm injection (ICSI) and in vitro fertilization (IVF) with fresh and cryopreserved testicular spermatozoa in patients with obstructive and nonobstructive azoospermia. Design: Retrospective analysis of consecutive ICSI cycles. Setting: Large urban reproductive medicine program. Patient(s): Twenty-nine patients with obstructive and nonobstructive azoospermia undergoing testicular sperm extraction for a total of 46 IVF-ICSI cycles (12 fresh, 34 frozen). Intervention(s): Testicular sperm extraction, cryopreservation, and IVF-ICSI with fresh or frozen-thawed spermatozoa. Main Outcome Measure(s): Fertilization rates, embryo cleavage rates, embryo implantation rates, clinical pregnancy rates per cycle and per embryo transfer, and delivery and spontaneous abortion rates. Result(s): No statistically significant differences were noted in any of the parameters examined between IVF-ICSI cycles from fresh or frozen-thawed testicular spermatozoa. Fertilization rates were 56% with fresh vs. 61% with frozen-thawed testicular sperm, cleavage rates 92% vs. 95%, implantation rates 26% vs. 17%, clinical pregnancy rates per cycle 33% vs; 41%, and pregnancy rates per embryo transfer 33% vs. 45%, respectively. Delivery rates were 75% with fresh vs. 69.2% with frozen-thawed testicular sperm, and spontaneous abortion rates 25% and 30.8%, respectively. Conclusion(s): No differences were found in IVF-ICSI outcomes between cryopreserved and fresh testicular sperm. In addition, cryopreservation provides several advantages for the patients and reproductive team. (Fertil Steril(R) 2000;73:955-60. (C) 2000 by American Society for Reproductive Medicine).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 08:20:58