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Titolo:
Plasmodium yoelii: Identification of a gene encoding a putative ADP-ribosylation factor-1 GTPase-activating protein, PyAG1
Autore:
Hienne, R; Rico, A; Parzy, D; Doury, JC;
Indirizzi:
Serv Sante Armees, Inst Trop Med, Unite Parasitol, F-13998 Marseille, France Serv Sante Armees Marseille France F-13998 ol, F-13998 Marseille, France
Titolo Testata:
MEMORIAS DO INSTITUTO OSWALDO CRUZ
fascicolo: 3, volume: 95, anno: 2000,
pagine: 345 - 352
SICI:
0074-0276(200005/06)95:3<345:PYIOAG>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
SECRETORY PATHWAY; RHOPTRY ORGANELLES; FALCIPARUM; PARASITE; ERYTHROCYTE; TRANSPORT; MEMBRANE; CLEFTS;
Keywords:
Plasmodium yoelii; gene PyAG1; immature rhoptries; vesicular transport;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Hienne, R Serv Sante Armees, Inst Trop Med, Unite Parasitol, Parc Pharo,BP46, F-13998 Marseille, France Serv Sante Armees Parc Pharo,BP 46 Marseille France F-13998 nce
Citazione:
R. Hienne et al., "Plasmodium yoelii: Identification of a gene encoding a putative ADP-ribosylation factor-1 GTPase-activating protein, PyAG1", MEM I OSW C, 95(3), 2000, pp. 345-352

Abstract

The PyAG1 gene, identified by the screening of a Plasmodium yoelii genomicDNA library with a rhoptry-specific Mab, encodes a protein with a zinc finger structure immediately followed by the consensus sequence of the Arf GAPcatalytic site. The serum of mice immunized with the recombinant protein recognized specifically the rhoptries of the late infected erythrocytic stages. Blast analysis using the Genbank database gave the highest scores with four proteins presenting an Arf1 GAP activity. If presenting also this activity the PyAG1 protein could be involved in the regulation of the secreted protein vesicular transport and, consequently in the rhoptry biogenesis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/21 alle ore 04:24:28