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Titolo:
Evidence for presence of Ig64 anti-immunoglobulin autoantibodies in all human beings
Autore:
Hennig, C; Rink, L; Kirchner, H;
Indirizzi:
Univ Lubeck, Sch Med, Inst Immunol & Transfus Med, D-23562 Lubeck, GermanyUniv Lubeck Lubeck Germany D-23562 Transfus Med, D-23562 Lubeck, Germany
Titolo Testata:
LANCET
fascicolo: 9215, volume: 355, anno: 2000,
pagine: 1617 - 1618
SICI:
0140-6736(20000506)355:9215<1617:EFPOIA>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
5
Recensione:
Indirizzi per estratti:
Indirizzo: Kirchner, H Univ Lubeck, Sch Med, Inst Immunol & Transfus Med, D-23562 Lubeck, Germany Univ Lubeck Lubeck Germany D-23562 , D-23562 Lubeck, Germany
Citazione:
C. Hennig et al., "Evidence for presence of Ig64 anti-immunoglobulin autoantibodies in all human beings", LANCET, 355(9215), 2000, pp. 1617-1618

Abstract

IgG4 anti-IgG autoantibodies were found to be present in all serum samplesfrom a group of healthy people; IgG4 anti-IgA and anti-IgE were present inonly 13 of 218 (6%) and 8 of 218 (3.5%) samples, respectively. These antibodies also showed affinities towards animal immunoglobulins. We suggest that IgG4 anti-IgA antibodies (the strongest found heterophilic immunoglobulins) are responsible for most artifacts obtained with commercial ELISA systems.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 07:49:25