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Titolo:
Distinguishing illness severity from tic severity in children and adolescents with Tourette's disorder
Autore:
Coffey, BJ; Biederman, J; Geller, DA; Spencer, TJ; Kim, GS; Bellordre, CA; Frazier, JA; Cradock, K; Magovcevic, M;
Indirizzi:
Harvard Univ, Sch Med, McLean Hosp, Joint Pediat Psychopharmacol Unit, Belmont, MA 02478 USA Harvard Univ Belmont MA USA 02478 hopharmacol Unit, Belmont, MA 02478 USA Harvard Univ, Sch Med, Massachusetts Gen Hosp, Joint Pediat Psychopharmacol Unit, Belmont, MA 02478 USA Harvard Univ Belmont MA USA 02478 hopharmacol Unit, Belmont, MA 02478 USA Harvard Univ, Sch Med, Dept Psychiat, Belmont, MA 02478 USA Harvard Univ Belmont MA USA 02478 d, Dept Psychiat, Belmont, MA 02478 USA
Titolo Testata:
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
fascicolo: 5, volume: 39, anno: 2000,
pagine: 556 - 561
SICI:
0890-8567(200005)39:5<556:DISFTS>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
PSYCHOPATHOLOGY; RELIABILITY; SCHEDULE; MANIA;
Keywords:
illness severity; tics; Tourette's disorder;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Coffey, BJ Harvard Univ, Sch Med, McLean Hosp, Joint Pediat Psychopharmacol Unit, 115Mill St, Belmont, MA 02478 USA Harvard Univ 115 Mill St Belmont MA USA 02478 ont, MA 02478 USA
Citazione:
B.J. Coffey et al., "Distinguishing illness severity from tic severity in children and adolescents with Tourette's disorder", J AM A CHIL, 39(5), 2000, pp. 556-561

Abstract

Objective: To examine whether tic severity, comorbid disorders, or both are associated with illness morbidity in youths with Tourette's disorder (TD). Method: Subjects were 156 consecutively referred youths (aged 5-20 years)who met DSM-III-R criteria for Tourette's disorder at a major academic medical center. All subjects were evaluated with a clinical interview by a child and adolescent psychiatrist and an assessment battery that included the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Epidemiologic version. Statistical analysis used chi(2) and multivariate logistic regression. Results: Nineteen (12%) of the 156 youths with TD required psychiatric hospitalization. Current age, TD severity, TD duration, obsessive-compulsive disorder, psychosis, major depression, bipolar disorder, panic disorder, and overanxious disorder were significant univariate predictors of psychiatric hospitalization (p < .01]. While tic severity was marginally significant as a predictor of psychiatric hospitalization (p < .05), major depression (p < .016) and bipolar disorder (p < .001) were robust predictors of psychiatric hospitalization, even after statistical adjustment far collinearity and correction for all other variables assessed. Conclusion:The findings indicate that comorbid mood disorders are strongly associatedwith illness morbidity in youths with TD, highlighting the importance of attention to comorbidity in patients with TD.

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Documento generato il 04/06/20 alle ore 01:18:46