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Titolo:
Risk analysis of treatment of unruptured aneurysms
Autore:
Mitchell, P; Jakubowski, J;
Indirizzi:
Royal Hallamshire Hosp, Dept Neurosurg, Sheffield S10 2JF, S Yorkshire, England Royal Hallamshire Hosp Sheffield S Yorkshire England S10 2JF ire, England
Titolo Testata:
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
fascicolo: 5, volume: 68, anno: 2000,
pagine: 577 - 580
SICI:
0022-3050(200005)68:5<577:RAOTOU>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRACRANIAL SACCULAR ANEURYSMS; CEREBRAL ANEURYSMS; DECISION-ANALYSIS; CONVENIENT APPROXIMATION; LIFE EXPECTANCY; MANAGEMENT; SURGERY; DEALE;
Keywords:
intracranial aneurysms; risk analysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Mitchell, P Royal Hallamshire Hosp, Dept Neurosurg, Glossop Rd, Sheffield S10 2JF, S Yorkshire, England Royal Hallamshire Hosp Glossop Rd Sheffield SYorkshire England S10 2JF
Citazione:
P. Mitchell e J. Jakubowski, "Risk analysis of treatment of unruptured aneurysms", J NE NE PSY, 68(5), 2000, pp. 577-580

Abstract

Objectives-To calculate the expected number of life-years saved by surgical treatment of unruptured intracranial aneurysms at ages over 20 years. Methods-An actuarial risk analysis of the treatment of unruptured intracranial aneurysms based on data from the International Study of Unruptured Intracranial Aneurysms (ISUIA). The benefits of operative treatment are calculated in terms of average life-years saved. Results-Results are presented as graphs of life-years saved or lost against age at the time of operative treatment for three groups of aneurysms: those under 10 mm in diameter with no history of subarachnoid haemorrhage (SAH) from another aneurysm, those under 10 mm in diameter and a history of previous SAH from a different aneurysm, and those over 10 mm in diameter. Life-years are lost at all ages in the group under 10 mm with no history of SAH. For the group under 10 mm with a history of SAH about 4 years are saved at age 20 declining to 0 at around age 50. For aneurysms 10 mm or more in diameter about 8 life-years are saved at age 20 declining to 0 at around 50. Conclusions-Clipping of unruptured aneurysms under 10 mm in diameter with no history of subarachnoid haemorrhage is not justified on actuarial grounds. Intervention in other unruptured aneurysms produces benefits in life expectancy up to the age of 50. There may be subgroups of aneurysms in which larger benefits exist.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 03:54:53