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Titolo: Variable pattern of visual recovery of Leber's hereditary optic neuropathy
Autore: Nakamura, M; Yamamoto, M;
- Indirizzi:
- Kobe Univ, Sch Med, Dept Ophthalmol, Kobe, Hyogo, Japan Kobe Univ Kobe Hyogo Japan Sch Med, Dept Ophthalmol, Kobe, Hyogo, Japan
- Titolo Testata:
- BRITISH JOURNAL OF OPHTHALMOLOGY
fascicolo: 5,
volume: 84,
anno: 2000,
pagine: 534 - 535
- SICI:
- 0007-1161(200005)84:5<534:VPOVRO>2.0.ZU;2-1
- Fonte:
- ISI
- Lingua:
- ENG
- Soggetto:
- CRITICAL FLICKER FREQUENCY; MUTATION; NEURITIS;
- Tipo documento:
- Article
- Natura:
- Periodico
- Settore Disciplinare:
- Clinical Medicine
- Life Sciences
- Citazioni:
- 10
- Recensione:
- Indirizzi per estratti:
- Indirizzo: Nakamura, M Penn State Univ, Coll Med, Dept Ophthalmol, H166,500 Univ Dr, Hershey, PA 17033 USA Penn State Univ H166,500 Univ Dr Hershey PA USA 170337033 USA
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- Citazione:
- M. Nakamura e M. Yamamoto, "Variable pattern of visual recovery of Leber's hereditary optic neuropathy", BR J OPHTH, 84(5), 2000, pp. 534-535
Abstract
Aims-To investigate pattern of visual recovery of nine patients with Leber's hereditary optic neuropathy (LHON) and a mitochondrial DNA mutation at 11778. Methods-Recovery was judged significant when a gain of two lines or more in the Landolt ring chart, 10 dB or more improvement of the mean deviation of static perimetry, or improvement of critical flicker frequency (CFF) over35 Hz was shown. Results-All three visual functions tested dramatically recovered in one patient. Two other patients exhibited isolated improvement of CFF or visual field, respectively. Conclusion-Partial improvement of visual function may be more widespread than previously recognised in LHON patients with the 11778 mutation.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 17:28:14