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Titolo:
Left ventricular assist device bridge therapy for acute myocardial infarction
Autore:
Park, SJ; Nguyen, DQ; Bank, AJ; Ormaza, S; Bolman, RM;
Indirizzi:
Univ Minnesota Hosp & Clin, Div Thorac & Cardiovasc Surg, Minneapolis, MN 55455 USA Univ Minnesota Hosp & Clin Minneapolis MN USA 55455 eapolis, MN 55455 USA
Titolo Testata:
ANNALS OF THORACIC SURGERY
fascicolo: 4, volume: 69, anno: 2000,
pagine: 1146 - 1151
SICI:
0003-4975(200004)69:4<1146:LVADBT>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
MECHANICAL CIRCULATORY SUPPORT; CARDIOGENIC-SHOCK; CARDIAC TRANSPLANTATION; HEART-FAILURE; IMPLANTATION; REPERFUSION; EXPERIENCE; RECOVERY; FUTURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Park, SJ Univ Minnesota, Div Thorac & Cardiovasc Surg, Box 207,420 Delaware St SE, Minneapolis, MN 55455 USA Univ Minnesota Box 207,420 Delaware St SE Minneapolis MN USA 55455
Citazione:
S.J. Park et al., "Left ventricular assist device bridge therapy for acute myocardial infarction", ANN THORAC, 69(4), 2000, pp. 1146-1151

Abstract

Background. Patients with acute myocardial infarction (AMI) complicated bycardiogenic shock have a high mortality rate. Current treatment modalitiesremain suboptimal for these patients. Methods. From April 1995 to March 1998, 7 patients were identified as having AMI associated with cardiogenic shock. All received intraaortic balloon pump assistance, in addition to maximal inotropic support. Results. The mean preoperative cardiac index was 2.0 +/- 0.3 L/min/m(2) and pulmonary capillary wedge pressure was 23 +/- 6 mm Hg. Three patients received thrombolytic therapy and 4 patients underwent percutaneous transluminal coronary angioplasty without success. Left ventricular assist devices (LVADs) were implanted as bridge therapy to heart transplantation. One patient died from recurrence of a ventricular septal defect during LVAD support. Six patients were transplanted successfully after mean LVAD support of 59 +/- 33 days. Five patients are alive and well at a mean follow-up of 898 +/-447 days. One patient died 3 days after transplantation from acute allograft dysfunction. Conclusions. Timely application of LVADs as bridge therapy to heart transplantation in these critically ill patients can be lifesaving, and should beinvestigated further. (C) 2000 by The Society of Thoracic Surgeons.

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Documento generato il 29/02/20 alle ore 15:01:38