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Titolo:
Effects of tilmicosin treatment on Pasteurella haemolytica organisms in nasal secretion specimens of calves with respiratory tract disease
Autore:
Frank, GH; Briggs, RE; Loan, RW; Purdy, CW; Zehr, ES;
Indirizzi:
USDA ARS, Natl Anim Dis Ctr, Ames, IA 50010 USA USDA ARS Ames IA USA 50010 SDA ARS, Natl Anim Dis Ctr, Ames, IA 50010 USA Texas A&M Univ, Texas Vet Med Ctr, Dept Vet Pathobiol, Coll Vet Med, College Stn, TX 77843 USA Texas A&M Univ College Stn TX USA 77843 et Med, College Stn, TX 77843 USA USDA ARS, Conservat & Prod Res Lab, Bushland, TX 79012 USA USDA ARS Bushland TX USA 79012 vat & Prod Res Lab, Bushland, TX 79012 USA
Titolo Testata:
AMERICAN JOURNAL OF VETERINARY RESEARCH
fascicolo: 5, volume: 61, anno: 2000,
pagine: 525 - 529
SICI:
0002-9645(200005)61:5<525:EOTTOP>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
MACROLIDE ANTIBIOTIC TILMICOSIN; CALF PNEUMONIA; INHIBITORY CONCENTRATION; COLONIZATION; EFFICACY; TONSILS; CATTLE; OXYTETRACYCLINE; NASOPHARYNX; VACCINATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Frank, GH USDA ARS, Natl Anim Dis Ctr, POB 70, Ames, IA 50010 USA USDA ARSPOB 70 Ames IA USA 50010 tr, POB 70, Ames, IA 50010 USA
Citazione:
G.H. Frank et al., "Effects of tilmicosin treatment on Pasteurella haemolytica organisms in nasal secretion specimens of calves with respiratory tract disease", AM J VET RE, 61(5), 2000, pp. 525-529

Abstract

Objective-To determine the effect of tilmicosin treatment on number of Pasteurella haemolytica (PH) organisms in nasal secretion specimens of calves with respiratory tract disease. Animals-206 British mixed-breed beef calves, 2 to 5 months old. Procedure-In 2 separate studies of outbreaks, calves (study 1, n = 101; study 2, n = 105) that developed respiratory tract disease after transport toa feedlot were treated with tilmicosin. Nasal secretion specimens were examined for PH organisms to determine the status of colonization. Results-In both studies, PH serotypes A1 and A6 were isolated. In study 1,tilmicosin treatment eliminated or markedly reduced the number of PH organisms in calves on days 1, 4, and 5 after treatment. In study 2, tilmicosin treatment eliminated PH organisms in calves on days 1, 2, 5, and 6 after treatment. Conclusions and Clinical Relevance-Overall, tilmicosin treatment increasedthe number of culture-positive calves that became culture-negative and decreased the number of culture-negative calves that became culture-positive for up to 6 days after treatment. Tilmicosin treatment decreased the number of PH organisms in nasal secretion specimens, which indicated that fewer PHorganisms were available to infect the lungs or to infect other calves. Byreducing colonization, prophylactic use of tilmicosin before transport or at the time of arrival at a feedlot is likely to reduce the incidence of acute respiratory tract disease in calves for the initial several days after arrival, which is the period when they are most susceptible to infectious organisms.

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Documento generato il 26/09/20 alle ore 10:42:32