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Titolo:
Saliva level of free 3-methoxy-4-hydroxyphenylglycol (MHPG) as a biological index of anxiety disorders
Autore:
Yamada, S; Yamauchi, K; Yajima, J; Hisadomi, S; Maeda, H; Toyomasu, K; Tanaka, M;
Indirizzi:
Kurume Univ, Sch Med, Inst Brain Dis, Kurume, Fukuoka 8300011, Japan Kurume Univ Kurume Fukuoka Japan 8300011 , Kurume, Fukuoka 8300011, Japan Kurume Univ, Sch Med, Dept Neuropsychiat, Kurume, Fukuoka 8300011, Japan Kurume Univ Kurume Fukuoka Japan 8300011 , Kurume, Fukuoka 8300011, Japan Kurume Univ, Sch Med, Fac Hlth & Phys Educ, Kurume, Fukuoka 8300011, JapanKurume Univ Kurume Fukuoka Japan 8300011 , Kurume, Fukuoka 8300011, Japan Kurume Univ, Inst Comparat Studies Int Cultures & Soc, Kurume, Fukuoka 8300011, Japan Kurume Univ Kurume Fukuoka Japan 8300011 , Kurume, Fukuoka 8300011, Japan
Titolo Testata:
PSYCHIATRY RESEARCH
fascicolo: 3, volume: 93, anno: 2000,
pagine: 217 - 223
SICI:
0165-1781(20000410)93:3<217:SLOF3(>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
URINARY FREE CORTISOL; NORADRENERGIC FUNCTION; PANIC DISORDER; PLASMA MHPG; CATECHOLAMINE METABOLITES; DEXAMETHASONE SUPPRESSION; DEPRESSIVE-DISORDERS; HEALTHY-SUBJECTS; STRESS; ESTRADIOL;
Keywords:
3-methoxy-4-hydroxyphenylglycol (MHPG); saliva; anxiety disorder; gender difference;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Yamada, S Kurume Univ, Sch Med, Inst Brain Dis, Asahi Machi 67, Kurume, Fukuoka 8300011, Japan Kurume Univ Asahi Machi 67 Kurume Fukuoka Japan 8300011 1, Japan
Citazione:
S. Yamada et al., "Saliva level of free 3-methoxy-4-hydroxyphenylglycol (MHPG) as a biological index of anxiety disorders", PSYCHIAT R, 93(3), 2000, pp. 217-223

Abstract

To access the saliva level of free 3-methoxy-4-hydroxyphenylglycol (MHPG) as a biological index of anxiety disorders, gender- or age-dependent changes in saliva MHPG level in patients with anxiety disorders were investigated. Saliva MHPG levels in 196 normal volunteers (59 male, 137 female) and 42 outpatients with anxiety disorders (20 male, 22 female) at the initial consultation to the hospital were measured by gas chromatography-mass spectrometry. Saliva MHPG levels in patients were higher than those in normal subjects. The increase in saliva MHPG levels in male patients was greater than that in female patients. Age-associated increase in the saliva MHPG level wasgreater in patients than in normal subjects. Especially, a significant interaction of age vs. patient effect was found in female subjects (P = 0.0005), but not in male subjects (P = 0.174). These data indicate that the measurement of saliva MHPG would be valuable for detecting pathological anxiety in male patients regardless of age and in older female patients, but not inyounger female patients. (C) 2000 Elsevier Science Ireland Ltd. All rightsreserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 23:02:27