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Titolo:
Treatment of hypertension in the diabetic patient
Autore:
Amar, J; Chamontin, B; Salvador, M;
Indirizzi:
CHU Purpan, Serv Med Interne & Hypertens Arterielle, F-31059 Toulouse, France CHU Purpan Toulouse France F-31059 Arterielle, F-31059 Toulouse, France
Titolo Testata:
PRESSE MEDICALE
fascicolo: 13, volume: 29, anno: 2000,
pagine: 749 - 755
SICI:
0755-4982(20000408)29:13<749:TOHITD>2.0.ZU;2-5
Fonte:
ISI
Lingua:
FRE
Soggetto:
CORONARY HEART-DISEASE; ISOLATED SYSTOLIC HYPERTENSION; CONVERTING ENZYME-INHIBITION; BLOOD-PRESSURE; MYOCARDIAL-INFARCTION; RANDOMIZED TRIAL; ANTIHYPERTENSIVE TREATMENT; CARDIOVASCULAR MORTALITY; PULSE PRESSURE; RENAL-FAILURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Amar, J CHU Purpan, Serv Med Interne & Hypertens Arterielle, F-31059 Toulouse, France CHU Purpan Toulouse France F-31059 lle, F-31059 Toulouse, France
Citazione:
J. Amar et al., "Treatment of hypertension in the diabetic patient", PRESSE MED, 29(13), 2000, pp. 749-755

Abstract

Blood pressure control: More than half of all diabetic patients have high blood pressure. Even more so than in the general population, hypertension compromises the cardiovascular and renal prognosis. Optimal blood pressure control can limit the progression of microangiopathy and macroangiopathy as clearly demonstrated in the HOT and UKPDS studies. For the WHO, the goal isto control pressures < 130/85 mmHg. In this respect, there has been no demonstration of a J-curve relationship between pressure lowering with antihypertension drugs and incidence of cardiovascular events among patients with coronary artery disease included in the HOT study. Multiple drug therapy: Regular longterm monitoring and, in most cases, multiple-drug regimens, are prerequisites for maintaining pressure figures below 130/85. When elaborating a blood pressure control protocol, it is important to consider the presence of coronary artery disease, suggesting use of beta blockers, or renal disease, which should lead to the use of angiotensin converting enzyme inhibitors. Diuretics play an important role in combination regimens and are indispensable in three-drug protocols or in case of altered renal function. Systolic hypertension: Subgroup analyses in the SHEP and SYST-EUR studies demonstrated the importance of treating pure systolic hypertension in diabetics. The protection obtained has the same or even more impact than in the general population. Risk factors: Diabetes control must of course be maintained and coherent management requires taking into consideration all the risk factors, especially smoking and dylipidemia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:27:41