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Titolo:
Functional MR evaluation of temporal and frontal language dominance compared with the Wada test
Autore:
Lehericy, S; Cohen, L; Bazin, B; Samson, S; Giacomini, E; Rougetet, R; Hertz-Pannier, L; Le Bihan, D; Marsault, C; Baulac, M;
Indirizzi:
Hop La Pitie Salpetriere, Dept Neuroradiol, F-75013 Paris, France Hop La Pitie Salpetriere Paris France F-75013 iol, F-75013 Paris, France Hop La Pitie Salpetriere, Dept Neurol, F-75013 Paris, France Hop La Pitie Salpetriere Paris France F-75013 rol, F-75013 Paris, France CEA, Serv Hosp Frederic Joliot, Dept Med Res, F-91406 Orsay, France CEA Orsay France F-91406 ric Joliot, Dept Med Res, F-91406 Orsay, France
Titolo Testata:
NEUROLOGY
fascicolo: 8, volume: 54, anno: 2000,
pagine: 1625 - 1633
SICI:
0028-3878(20000425)54:8<1625:FMEOTA>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT PLANUM TEMPORALE; PREFRONTAL CORTEX; WORD GENERATION; HUMAN BRAIN; PET; RETRIEVAL; ASYMMETRY; ANATOMY; MEMORY; COMPREHENSION;
Keywords:
functional MRI; language; epilepsy; hemispheric dominance;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
46
Recensione:
Indirizzi per estratti:
Indirizzo: Lehericy, S Hop La Pitie Salpetriere, Dept Neuroradiol, Batiment Babinski,47 Bd Hop, F-75013 Paris, France Hop La Pitie Salpetriere Batiment Babinski,47 Bd Hop Paris France F-75013
Citazione:
S. Lehericy et al., "Functional MR evaluation of temporal and frontal language dominance compared with the Wada test", NEUROLOGY, 54(8), 2000, pp. 1625-1633

Abstract

Objective: To evaluate the reliability of temporal and frontal functional MRI (fMRI) activation for the assessment of language dominance, as comparedwith the Wada test. Patients and Methods: Ten patients;with temporal lobe epilepsy were studied using blood oxygen level dependent fMRI and echoplanar imaging (1.5-T). Three tasks were used: semantic verbal fluency, covert sentence repetition, and story listening. Data were analyzed using pixel by pixel autocorrelation and cross-correlation. fMRI laterality indices were defined for several regions of interest as the ratio (L - R)/(L + R), L being the number of activated voxels in the left hemisphere and R in the right hemisphere. Wada laterality indices were defined as the difference in the percentages of errors in language tests between left and right carotid injections. Results: Semantic verbal fluency: The asymmetry of frontal activation was correlated with Wada laterality indices. The strongest correlation was observed in the precentral/middle frontal gyrus/inferior frontal sulcus area. Story listening: The asymmetry of frontal, but not temporal, activation was correlated with Wada laterality indices. Covert sentence repetition: No correlation was observed. Conclusions: There was a good congruence between hemispheric dominance for language as assessed with the Wada test and fMRI laterality indices in the frontal but not in the temporal lobes. The story listening and the covert sentence repetition tasks increased the sensitivity of detection of posterior language sites that may be useful for brain lesion surgery.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 12:57:17