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Titolo:
Developmental changes in cerebrospinal fluid concentrations of monoamine-related substances revealed with a Coulochem electrode array system
Autore:
Takeuchi, Y; Matsushita, H; Sakai, H; Kawano, H; Yoshimoto, K; Sawada, T;
Indirizzi:
Kyoto Prefectural Univ Med, Dept Pediat, Kamikyo Ku, Kyoto 6028566, Japan Kyoto Prefectural Univ Med Kyoto Japan 6028566 Ku, Kyoto 6028566, Japan Kyoto Prefectural Univ Med, Dept Legal Med, Kamikyo Ku, Kyoto 6028566, Japan Kyoto Prefectural Univ Med Kyoto Japan 6028566 Ku, Kyoto 6028566, Japan
Titolo Testata:
JOURNAL OF CHILD NEUROLOGY
fascicolo: 4, volume: 15, anno: 2000,
pagine: 267 - 270
SICI:
0883-0738(200004)15:4<267:DCICFC>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
KYNURENIC ACID; METABOLITES; NEUROTRANSMITTERS; SEROTONIN; DOPAMINE; CHILDREN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Takeuchi, Y Kyoto Prefectural Univ Med, Dept Pediat, Kamikyo Ku, Kyoto 6028566, Japan Kyoto Prefectural Univ Med Kyoto Japan 6028566 028566, Japan
Citazione:
Y. Takeuchi et al., "Developmental changes in cerebrospinal fluid concentrations of monoamine-related substances revealed with a Coulochem electrode array system", J CHILD NEU, 15(4), 2000, pp. 267-270

Abstract

The relationship between age and cerebrospinal fluid concentrations of monoamine-related substances, including kynurenine, were investigated using a Coulochem electrode array system, to clarify developmental changes in monoamine-related substances in the human central nervous system. Ln neurologically normal children, significant inverse correlations with age were observed for the cerebrospinal fluid concentrations of 5-hydroxytryptophan, 5-hydroxyindole-acetic acid, kynurenine, homovanillic acid, 3-methoxy-4-hydroxyphenyl glycol, and 3-O-methyl-dopamine. The concentrations of their precursors, tryptophan and tyrosine, were not related to age. This is the first comprehensive study revealing developmental changes in monoamine-related substances including their precursors and metabolites.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 00:00:42