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Titolo:
Characterisation of calmodulin binding to cyclic nucleotide-gated ion channels from Arabidopsis thaliana
Autore:
Kohler, C; Neuhaus, G;
Indirizzi:
Univ Freiburg, Inst Biol Zellbiol 2, D-79104 Freiburg, Germany Univ Freiburg Freiburg Germany D-79104 biol 2, D-79104 Freiburg, Germany
Titolo Testata:
FEBS LETTERS
fascicolo: 2-3, volume: 471, anno: 2000,
pagine: 133 - 136
SICI:
0014-5793(20000414)471:2-3<133:COCBTC>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIVERGENT MESSENGER-RNAS; PHOTORECEPTOR CELLS; CALCIUM-CALMODULIN; CATION CHANNEL; BETA-SUBUNIT; IDENTIFICATION; MODULATION;
Keywords:
cyclic nucleotide-gated ion channel; calmodulin binding site; non-radioactive calmodulin overlay assay; calmodulin isoform; two-hybrid assay; Arabidopsis thaliana;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Neuhaus, G Univ Freiburg, Inst Biol Zellbiol 2, Schanzlestr 1, D-79104 Freiburg, Germany Univ Freiburg Schanzlestr 1 Freiburg Germany D-79104 , Germany
Citazione:
C. Kohler e G. Neuhaus, "Characterisation of calmodulin binding to cyclic nucleotide-gated ion channels from Arabidopsis thaliana", FEBS LETTER, 471(2-3), 2000, pp. 133-136

Abstract

The recently identified cyclic nucleotide-gated ion channels (AtCNGCs) from Arabidopsis have the ability to bind calmodulin, Using two different methods, we mapped the binding site of AtCKGC1 to the last predicted alpha helix of the cyclic nuclcotide binding domain. This is in contrast to CNGCs from animals, where the calmodulin binding site is located in the N-terminus, implying that different mechanisms for CNGC modulation have evolved in animals and plants, Furthermore, we demonstrate that AtCNGC1 and AtCNGC2 have different calmodulin binding affinities and ne provide evidence for target specificities among calmodulin isoforms. (C) 2000 Federation of European Biochemical Societies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 15:22:24