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Titolo:
Clinical manifestations of Korean female gouty patients
Autore:
Park, YB; Park, YS; Song, J; Lee, WK; Suh, CH; Lee, SK;
Indirizzi:
Yonsei Univ, Coll Med, Dept Internal Med, Div Rheumatol, Seoul, South Korea Yonsei Univ Seoul South Korea al Med, Div Rheumatol, Seoul, South Korea
Titolo Testata:
CLINICAL RHEUMATOLOGY
fascicolo: 2, volume: 19, anno: 2000,
pagine: 142 - 146
SICI:
0770-3198(2000)19:2<142:CMOKFG>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
CYCLOSPORINE; HYPERURICEMIA; RECIPIENTS; ARTHRITIS; SPECTRUM; WOMEN;
Keywords:
female; gout; transplantation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Lee, SK Yonsei Univ, Coll Med, Dept Internal Med, Div Rheumatol, CPO Box 8044, Seoul, South Korea Yonsei Univ CPO Box 8044 Seoul South Korea 4, Seoul, South Korea
Citazione:
Y.B. Park et al., "Clinical manifestations of Korean female gouty patients", CLIN RHEUMA, 19(2), 2000, pp. 142-146

Abstract

In an endeavor to analyse the clinical characteristics of female gout, we reviewed 36 women with gout. Twenty-seven (75%) developed the first symptomatic episode of gout after the onset of the menopause. The mean age at onset of gout was 54.3 years (range 15-87 years). Twenty-two patients (61%) hadhypertension, 17 (47%) had renal insufficiency, 13 (36%) used diuretics and 10 (28%) were taking cyclosporine for a renal allograft. Tophaceous gout occurred in 10 patients (27%) and polyarticular involvement was seen in 16 (44%) at initial presentation. Five of nine premenopausal patients were taking cyclosporine and four had renal insufficiency. A comparison with a control group of 72 randomly selected male patients with gout showed that the female patients were frequently receiving diuretics at the time of the attack and had significantly lower mean uric acid excretion, whereas significantly more male patients showed heavy alcohol consumption and precipitating events for an acute attack compared with the female patients. There were no significant differences between the sexes for onset age, hypertension, renalinsufficiency, distribution of joint involvement, tophi and mean serum uric acid concentration. The female patients in this study had a lower mean age at onset of gout than in previous studies, which was attributed to the inclusion of renal transplantation patients. Transplantation gout patients receiving cyclosporine lower the mean age at onset of female gout and this isan emerging problem in female gout.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 11:19:10