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Titolo:
Chronic infiltrative lung diseases - Value of gadolinium-enhanced MRI in the evaluation of disease activity - Early report
Autore:
Gaeta, M; Blandino, A; Scribano, E; Minutoli, F; Barone, M; Ando, F; Pandolfo, I;
Indirizzi:
Univ Messina, Inst Sci Radiol, Messina, Italy Univ Messina Messina Italy niv Messina, Inst Sci Radiol, Messina, Italy Univ Messina, Inst Chirurg Toracica, Messina, Italy Univ Messina MessinaItaly ssina, Inst Chirurg Toracica, Messina, Italy Univ Messina, Inst Malattie Resp, Messina, Italy Univ Messina Messina Italy Messina, Inst Malattie Resp, Messina, Italy
Titolo Testata:
CHEST
fascicolo: 4, volume: 117, anno: 2000,
pagine: 1173 - 1178
SICI:
0012-3692(200004)117:4<1173:CILD-V>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
GROUND-GLASS ATTENUATION; PULMONARY SARCOIDOSIS; BRONCHOALVEOLAR LAVAGE; CT;
Keywords:
chronic infiltrative lung disease; disease activity; gadolinium; lung; MRI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Minutoli, F Viale Tigli 25, I-98168 Messina, Italy Viale Tigli 25 Messina Italy I-98168 I-98168 Messina, Italy
Citazione:
M. Gaeta et al., "Chronic infiltrative lung diseases - Value of gadolinium-enhanced MRI in the evaluation of disease activity - Early report", CHEST, 117(4), 2000, pp. 1173-1178

Abstract

Study objective: To determine the value of gadolinium-enhanced MRI in the assessment of disease activity in chronic infiltrative lung diseases (CILDs). Design: Retrospective study,Setting: University hospital,Materials and Methods:: Twenty-five consecutive patients with GILD were studied. The following diseases were diagnosed: sarcoidosis (n = 10), bronchiolitis obliterans organizing pneumonia (n = 3), usual interstitial pneumonia (n = 4), radiation pneumonia (n = 2), desquamative interstitial pneumonia(n = 1), rheumatoid lung (n = 1), vasculitis (n = 1), alveolar proteinosis(n = 1), bronchioloalveolar carcinoma (n = 1), and chronic eosinophilic pneumonia (n = 1). In each patient, the disease activity was assessed by one or more of the following studies: BAL (n = 18), gallium-radioisotope lung scanning(n = 6), serum angiotensin-converting enzyme assay (n = 10), and ol,en lung biopsy (n = 4), T1-weighted breath-hold MRI studies were obtained before and after IV injection of gadolinium. The MRI examinations were analyzed to assess the presence or absence of lesional enhancement. Results: The presence of enhanced pulmonary lesions was seen in 14 patients, All of these patients had active disease. Of the 17 patients with activedisease, 14 had enhanced lesions, and 3 had unenhanced lesions. Pulmonary lesions were not enhanced in any patients with inactive disease, The difference was statistically significant (Fisher Exact Test, p < 0.05),Conclusion: Gadolinium-enhanced MRI may prove to be a useful tool in assessing disease activity in CILDs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 08:21:45