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Titolo:
Contributions of the AmpC beta-lactamase and the AcrAB multidrug efflux system in intrinsic resistance of Escherichia coli K-12 to beta-lactams
Autore:
Mazzariol, A; Cornaglia, G; Nikaido, H;
Indirizzi:
Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA Univ Calif Berkeley Berkeley CA USA 94720 ll Biol, Berkeley, CA 94720 USA Univ Verona, Inst Microbiol, I-37100 Verona, Italy Univ Verona Verona Italy I-37100 , Inst Microbiol, I-37100 Verona, Italy
Titolo Testata:
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
fascicolo: 5, volume: 44, anno: 2000,
pagine: 1387 - 1390
SICI:
0066-4804(200005)44:5<1387:COTABA>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
OUTER-MEMBRANE PERMEABILITY; PSEUDOMONAS-AERUGINOSA; KINETIC-PARAMETERS; CEPHALOSPORINS; PENICILLINS; BACTERIA; PROTEINS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Nikaido, H Univ Calif Berkeley, Dept Mol & Cell Biol, Room 229,Stanley Hall, Berkeley, CA 94720 USA Univ Calif Berkeley Room 229,Stanley Hall Berkeley CA USA 94720
Citazione:
A. Mazzariol et al., "Contributions of the AmpC beta-lactamase and the AcrAB multidrug efflux system in intrinsic resistance of Escherichia coli K-12 to beta-lactams", ANTIM AG CH, 44(5), 2000, pp. 1387-1390

Abstract

The roles of the AmpC chromosomal beta-lactamase and the AcrAB efflux system in levels of intrinsic resistance and susceptibility of Escherichia colito beta-lactams were studied with a set of isogenic strains. MICs of ureidopenicillins, carbenicillin, oxacillin, and cloxacillin were drastically reduced by the inactivation of AcrAB, whereas those of the earlier cephalosporins were affected mostly by the loss of AmpC beta-lactamase.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 15:42:31