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Titolo:
A new preadmission staging system for predicting inpatient mortality from HIV-associated Pneumocystis carinii pneumonia in the early highly active antiretroviral therapy (HAART) era
Autore:
Arozullah, AM; Yarnold, PR; Weinstein, RA; Nwadiaro, N; McIlraith, TB; Chmiel, JS; Sipler, AM; Chan, CL; Goetz, MB; Schwartz, DN; Bennett, CL;
Indirizzi:
VA Chicago Hlth Care Syst, Lakeside Div, Chicago, IL 60611 USA VA Chicago Hlth Care Syst Chicago IL USA 60611 Div, Chicago, IL 60611 USA Brockton W Roxbury Vet Affairs Med Ctr, W Roxbury, MA USA Brockton W Roxbury Vet Affairs Med Ctr W Roxbury MA USA Roxbury, MA USA Edward Hines Vet Adm Med Ctr, Cooperat Studies Program Coordinating Ctr, Hines, IL 60141 USA Edward Hines Vet Adm Med Ctr Hines IL USA 60141 Ctr, Hines, IL 60141 USA Univ Illinois, Coll Med, Dept Med, Chicago, IL USA Univ Illinois Chicago IL USA linois, Coll Med, Dept Med, Chicago, IL USA Northwestern Univ, Sch Med, Dept Med, Chicago, IL 60611 USA Northwestern Univ Chicago IL USA 60611 d, Dept Med, Chicago, IL 60611 USA Northwestern Univ, Sch Med, Dept Prevent Med, Chicago, IL USA NorthwesternUniv Chicago IL USA Med, Dept Prevent Med, Chicago, IL USA Univ Illinois, Dept Psychol, Chicago, IL 60680 USA Univ Illinois Chicago IL USA 60680 s, Dept Psychol, Chicago, IL 60680 USA Cook Cty Hosp, Chicago, IL 60612 USA Cook Cty Hosp Chicago IL USA 60612Cook Cty Hosp, Chicago, IL 60612 USA VA Greater Los Angeles Healthcare Syst, Dept Med, Los Angeles, CA USA VA Greater Los Angeles Healthcare Syst Los Angeles CA USA ngeles, CA USA Univ Calif Los Angeles, Sch Med, Los Angeles, CA USA Univ Calif Los Angeles Los Angeles CA USA , Sch Med, Los Angeles, CA USA
Titolo Testata:
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
fascicolo: 4, volume: 161, anno: 2000,
pagine: 1081 - 1086
SICI:
1073-449X(200004)161:4<1081:ANPSSF>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACQUIRED-IMMUNODEFICIENCY-SYNDROME; IN-HOSPITAL MORTALITY; CLASSIFICATION TREE ANALYSIS; SERUM LACTATE-DEHYDROGENASE; AIDS PATIENTS; EXAMPLE; LONDON; CARE; PCP;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Bennett, CL VA Chicago Hlth Care Syst, Lakeside Div, 400 E Ontario St, Chicago, IL 60611 USA VA Chicago Hlth Care Syst 400 E Ontario St Chicago IL USA 60611
Citazione:
A.M. Arozullah et al., "A new preadmission staging system for predicting inpatient mortality from HIV-associated Pneumocystis carinii pneumonia in the early highly active antiretroviral therapy (HAART) era", AM J R CRIT, 161(4), 2000, pp. 1081-1086

Abstract

A common severe complication of human immunodeficiency virus (HIV) infection has been Pneumocystis carinii pneumonia (PCP). Recently, with increasinguse of PCP prophylaxis and multidrug antiretroviral therapy, the clinical manifestations of HIV infection have changed dramatically and the predictors of inpatient mortality for PCP may have also changed. We developed a new staging system for predicting inpatient mortality for patients with HIV-associated PCP admitted between 1995 and 1997. Trained abstractors per formed chart reviews of 1,660 patients hospitalized with HIV-associated PCP between 1995 and 1997 at 78 hospitals in seven metropolitan areas in the United States. The overall inpatient mortality rate was 11.3%. Hierarchically optimal classification tree analysis identified an ordered five-category stagingsystem based on three predictors: wasting, alveolar-arterial oxygen gradient (AaPo(2)), and serum albumin level. The mortality rate increased with stage: 3.7% for Stage 1, 8.5% for Stage 2, 16.1% for Stage 3, 23.3% for Stage4, and 49.1% for Stage 5. This new staging system may be useful for severity of illness adjustment in the current era while exploring current variation in HIV-associated PCP inpatient mortality rates among hospitals and across cities.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 05:51:39