Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Reactive hyperemia in skin after cardiopulmonary bypass
Autore:
Gruber, EM; Schwarz, B; Germann, R; Breuss, M; Bonatti, J; Hasibeder, W;
Indirizzi:
Innsbruck Univ, Dept Anesthesiol & Intens Care Med, A-6020 Innsbruck, Austria Innsbruck Univ Innsbruck Austria A-6020 e Med, A-6020 Innsbruck, Austria Innsbruck Univ, Dept Cardiothorac Surg, A-6020 Innsbruck, Austria Innsbruck Univ Innsbruck Austria A-6020 Surg, A-6020 Innsbruck, Austria Univ Vienna, Dept Cardiothorac & Vasc Anesthesia & Intens Care, Vienna, Austria Univ Vienna Vienna Austria sc Anesthesia & Intens Care, Vienna, Austria
Titolo Testata:
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
fascicolo: 2, volume: 14, anno: 2000,
pagine: 161 - 165
SICI:
1053-0770(200004)14:2<161:RHISAC>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
FREE-RADICAL GENERATION; SKELETAL-MUSCLE; CARDIAC-SURGERY; BLOOD-FLOW; OXYGEN; ADENOSINE; PROSTAGLANDINS; CIRCULATION; PERFUSION; INJURY;
Keywords:
reactive hyperemia; transcutaneous PO2; trans-cutaneous PCO2; CO2 elimination; skin microvascular hemoglobin saturation; cardiopulmonary bypass;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Gruber, EM AKH, Dept Cardothorac & Vasc Anesthesia & Intens Care, Waehringer Guertel 18-20, A-1090 Vienna, Austria AKH Waehringer Guertel 18-20 Vienna Austria A-1090 na, Austria
Citazione:
E.M. Gruber et al., "Reactive hyperemia in skin after cardiopulmonary bypass", J CARDIOTHO, 14(2), 2000, pp. 161-165

Abstract

Objective:To study reactive hyperemia (RH) using a transcutaneous PO2/PCO2combination electrode heated to 37 degrees C and tissue reflectance spectrophotometry in patients before and after cardiopulmonary bypass (CPB) to determine whether microcirculatory function of skin is altered. Design: Prospective study. Setting: Anesthesiology and critical care unit of a university hospital. Participants: Eight patients undergoing elective CPB under mild hypothermia. Interventions: To produce RH, blood flow to the forearm was prevented by inflation of a cuff to 300 mmHg for an interval of 5 minutes. Measurements and Main Results: Measurements were obtained on the day priorto surgery (DPS), on the day of surgery (DOS) rewarmed to 37 degrees C in the intensive care unit (ICU), and on the first (POD 1) and the third postoperative days (POD 3). The following parameters were recorded: preocclusivebaseline cutaneous PO2, and PCO2 (B-PtcO(2), B-PtcCO(2)), and microvascular hemoglobin saturation (B-HbO(2)); postischemic peak of PtcO(2), PtcCO(2),and HbO(2) and 10 minutes after release of the cuff occlusion posthyperemic PtcO(2), PtcCO(2), and HbO(2). B-PtcO(2) was 3.5 +/- 1.2 mmHg on DPS, 2.6+/- 0.7 mmHg on DOS, 1.5 +/- 0.3 mmHg on POD 1, and 3.5 +/- 3.5 mmHg on POD 3. B-PtcCO(2) increased significantly from 40.1 +/- 2.5 mmHg to 52.2 +/- 2.0 mmHg on DOS (p = 0.01) and to 48.9 +/- 3.6 mmHg on POD 1 Ip = 0.02). OnPOD 3 B-PtcCO(2) was 40.6 +/- 2.6 mmHg. B-HbO(2) declined from a preoperative value of 42.4% 8.6% to 37.1% +/- 14.7% on DOS and further to 21.7% +/- 4.8% on POD 1, which was significantly different Ip = 0.03). On POD 3, B-HbO(2) still remained lower (30.7% 6.2%) compared with the preoperative value. RH (Delta PtcO(2), Delta HBO2) was quantified as the differences between peak PtcO(2), HBO2 and B-PtcO(2), B-HBO2. Delta PtcO(2) was 13.0 +/- 2.3 onDPS. 11.3 +/- 2.9 on DOS. 12.6 +/- 2.6 on POD 1, and 11.5 +/- 3.5 on POD 3. Delta HBO2 was 42.0 +/- 5.6 on DPS, 40.0 +/- 7.1 on DOS, 49.9 +/- 2.5 on POD 1, and 52.9 +/- 6.4 on POD 3. The elimination rate of carbon dioxide from skin (ECO2) was calculated as difference between peak PtcCO(2) and PtcCO(2) after 3 minutes of reperfusion divided by the difference between peak PtcCO(2) and B-PtcCO(2). ECO2 was 1.0 +/- 0.2 kPa/min on DPS. 0.7 +/- 0.1 kPa/min on DOS, and 0.8 +/- 0.1 kPa/min on POD 1 and POD 3. Conclusion: Cutaneous microcirculation assessed by RH is well preserved during the immediate postoperative period in patients undergoing uncomplicated coronary artery surgery with CPB. Copyright (C) 2000 by W.B. Saunders Company

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 00:27:53