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Titolo:
AUTISM AND CELIAC-DISEASE - FAILURE TO VALIDATE THE HYPOTHESIS THAT ALINK MIGHT EXIST
Autore:
PAVONE L; FIUMARA A; BOTTARO G; MAZZONE D; COLEMAN M;
Indirizzi:
270 GLENWOOD RD LAKE FOREST IL 60045 UNIV CATANIA,PEDIAT CLIN CATANIA ITALY GEORGETOWN UNIV WASHINGTON DC 00000
Titolo Testata:
Biological psychiatry
fascicolo: 1, volume: 42, anno: 1997,
pagine: 72 - 75
SICI:
0006-3223(1997)42:1<72:AAC-FT>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Keywords:
AUTISM; CELIAC DISEASE; GLUTEN INTOLERANCE; ANTIGLIADIN ANTIBODIES; ANTIENDOMISIUM ANTIBODIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
L. Pavone et al., "AUTISM AND CELIAC-DISEASE - FAILURE TO VALIDATE THE HYPOTHESIS THAT ALINK MIGHT EXIST", Biological psychiatry, 42(1), 1997, pp. 72-75

Abstract

Autism is a heterogeneous condition and the possible pathogenic role of several different factors has been postulated. Association between celiac disease and neurological manifestations such as drug resistant epilepsy and cerebral calcifications is well known. Some authors in the past also reported the existence of a linkage with autism. On the basis of these observations, we have evaluated 120 patients with celiac disease diagnosed at the Pediatric Clinic of the University of Catania, Italy, in order to identify behavioral problems and autistic features; there were 20 controls for this parr of the study. At the same time, AGA and AEMAb were assayed in 11 patients with infantile autism and 11 age- and sex-matched controls. No celiac case was detected among the group of autistic patients and, although two of them had slightly increased levels of AGA Ige and AEMAb, subsequent antibodies determinations and jejunal biopsies gave normal results. Moreover none of the celiac patients had a positive DSM-III-R test for infantile autism. (C) 1997 Society of Biological Psychiatry.

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Documento generato il 26/11/20 alle ore 08:22:46