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Titolo:
Therapeutic drug monitoring of atypical antipsychotics - Is it of potential clinical value?
Autore:
Perry, PJ;
Indirizzi:
Univ Iowa, Coll Pharm, Div Clin Adm Pharm, Iowa City, IA 52242 USA Univ Iowa Iowa City IA USA 52242 Clin Adm Pharm, Iowa City, IA 52242 USA Univ Iowa, Coll Med, Dept Psychiat, Iowa City, IA 52242 USA Univ Iowa Iowa City IA USA 52242 , Dept Psychiat, Iowa City, IA 52242 USA
Titolo Testata:
CNS DRUGS
fascicolo: 3, volume: 13, anno: 2000,
pagine: 167 - 171
SICI:
1172-7047(200003)13:3<167:TDMOAA>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
REFRACTORY SCHIZOPHRENIC-PATIENTS; PLASMA CLOZAPINE CONCENTRATIONS; N-DESMETHYLCLOZAPINE; RISPERIDONE; METABOLITE; OLANZAPINE; EFFICACY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Perry, PJ Univ Iowa, Coll Pharm, Div Clin Adm Pharm, S-415 Pharm Bldg, Iowa City, IA52242 USA Univ Iowa S-415 Pharm Bldg Iowa City IA USA 52242 y, IA52242 USA
Citazione:
P.J. Perry, "Therapeutic drug monitoring of atypical antipsychotics - Is it of potential clinical value?", CNS DRUGS, 13(3), 2000, pp. 167-171

Abstract

Despite its cost, therapeutic drug monitoring for the atypical antipsychotics is of clinical value as it affords the opportunity to reduce toxicity and increase compliance. Although data document the utility of routine monitoring of blood clozapine and olanzapine concentrations, there are no similar data available for either risperidone or quetiapine. Numerous studies have established an ideal lower therapeutic threshold plasma concentration forclozapine while fewer data are available for olanzapine.

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Documento generato il 17/01/20 alle ore 21:13:17