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Titolo:
The abasic site as a target for generation of locally multiply damaged sites
Autore:
Martelli, A; Berthet, N; Constant, JF; Demeunynck, M; Lhomme, J;
Indirizzi:
Univ Grenoble 1, CNRS, LEDSS, UMR 5616, F-38041 Grenoble 9, France Univ Grenoble 1 Grenoble France 9 , UMR 5616, F-38041 Grenoble 9, France
Titolo Testata:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
fascicolo: 8, volume: 10, anno: 2000,
pagine: 763 - 766
SICI:
0960-894X(20000417)10:8<763:TASAAT>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
CLEAVE APURINIC SITES; DNA; ENDONUCLEASE; MECHANISMS; RECOGNIZE; REPAIR; MODEL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Constant, JF Univ Grenoble 1, CNRS, LEDSS, UMR 5616, BP 53, F-38041 Grenoble 9, France Univ Grenoble 1 BP 53 Grenoble France 9 1 Grenoble 9, France
Citazione:
A. Martelli et al., "The abasic site as a target for generation of locally multiply damaged sites", BIOORG MED, 10(8), 2000, pp. 763-766

Abstract

Abasic sites in DNA have been specifically targeted by synthetic compoundsable to cleave DNA at abasic sites and to induce photodamages in the vicinity of the lesion. The synthesis and the photoactivity of the drugs on abasic sites containing DNA and oligonucleotides are reported. (C) 2000 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 13:46:48