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Titolo:
Learning performance of normal and mutant Drosophila after repeated conditioning trials with discrete stimuli
Autore:
Beck, CDO; Schroeder, B; Davis, RL;
Indirizzi:
Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Dept Psychiat & Behav Sci, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 t & Behav Sci, Houston, TX 77030 USA
Titolo Testata:
JOURNAL OF NEUROSCIENCE
fascicolo: 8, volume: 20, anno: 2000,
pagine: 2944 - 2953
SICI:
0270-6474(20000415)20:8<2944:LPONAM>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CYCLIC-AMP PHOSPHODIESTERASE; MUSHROOM BODIES; PREFERENTIAL EXPRESSION; LATENT INHIBITION; PROTEIN-KINASE; TERM-MEMORY; DUNCE; GENE; MELANOGASTER; APLYSIA;
Keywords:
Drosophila; olfactory conditioning; massed training; spaced training; learning mutant; acquisition;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Davis, RL Baylor Coll Med, Dept Mol & Cellular Biol, 1 Baylor Plaza, Houston, TX 77030 USA Baylor Coll Med 1 Baylor Plaza Houston TX USA 77030 TX 77030 USA
Citazione:
C.D.O. Beck et al., "Learning performance of normal and mutant Drosophila after repeated conditioning trials with discrete stimuli", J NEUROSC, 20(8), 2000, pp. 2944-2953

Abstract

A new olfactory conditioning procedure is described using short training trials with discrete presentation of conditioned stimuli (CS) and unconditioned stimuli (US). A short odor presentation along with a single-shock stimulus produced modest but reliable and reproducible learning. Multiple trialspresented sequentially improved performance with increasing trial number. Trial spacing had a significant impact on performance. Two trials presentedwith a short intertrial interval (ITI) produced no improvement over a single trial; two trials with a 15 min ITI significantly boosted performance. This effect required two associative trials, because substituting one of thetrials with the CS alone, US alone, or an unpaired CS-US failed to boost performance. The increase in initial performance with two trials decayed within 15 min after training. Thus, the effect is short-lived. The utility of using a battery of tests, including a single short trial, two massed trials, and two spaced trials, to investigate parameters of memory formation in several mutants was demonstrated.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 07:38:17