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Titolo:
Prognosis in bronchogenic squamous cell carcinoma groups divided accordingto serum squamous cell carcinoma-related antigen and cytokeratin 19 fragment levels
Autore:
Kashiwabara, K; Nakamura, H; Esaki, T;
Indirizzi:
Taragi Municipal Hosp, Resp Dept, Kumamoto 8680501, Japan Taragi MunicipalHosp Kumamoto Japan 8680501 pt, Kumamoto 8680501, Japan Univ Tokyo, Dept Internal Med 5, Tokyo, Japan Univ Tokyo Tokyo JapanUniv Tokyo, Dept Internal Med 5, Tokyo, Japan
Titolo Testata:
CLINICA CHIMICA ACTA
fascicolo: 1-2, volume: 294, anno: 2000,
pagine: 105 - 113
SICI:
0009-8981(200004)294:1-2<105:PIBSCC>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
LUNG-CANCER; TUMOR-MARKER; CYFRA 21-1; SCC-AG; DIAGNOSIS; DISEASES; TPA;
Keywords:
lymph node metastasis; distant metastasis; indication for surgery; two-year survival rates; carcinoembryonic antigen;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Kashiwabara, K Taragi Municipal Hosp, Resp Dept, 4210 Taragi Machi, Kumamoto 8680501, Japan Taragi Municipal Hosp 4210 Taragi Machi Kumamoto Japan 8680501
Citazione:
K. Kashiwabara et al., "Prognosis in bronchogenic squamous cell carcinoma groups divided accordingto serum squamous cell carcinoma-related antigen and cytokeratin 19 fragment levels", CLIN CHIM A, 294(1-2), 2000, pp. 105-113

Abstract

We examined differences in the 2-year survival rate in bronchogenic squamous cell carcinoma patients with normal serum levels of both cytokeratin 19 fragment (CYFRA 21-1) and squamous cell carcinoma-related antigen (SCC) (NLgroup, n = 15), patients with only increased SCC levels (SCC + group, n = 14), patients with only increased CYFRA 21-1 levels (CYFRA + group, n = 14), and patients with elevated levels of both CYFRA 21-1 and SCC (EL group, n= 65). The 2-year survival rates for the CYFRA + and the EL group were lower than those for the SCC + group and the NL group (0 and 12.9% vs. 66.7 and 85.6%, log rank: p < 0.0001, Wilcoxon: p < 0.0001). However, there were no differences between the rate for the SCC + and the NL group and between that for the CYFRA + and the EL group. Serum carcinoembryonic antigen (CEA) levels increased in the patients with the elevated CYFRA 21-1 levels. This results suggest that there may be some differences between squamous cell carcinoma patients with increased CYFRA 21-1 levels and those with normal levels and that it is CYFRA 21-1 levels, not SCC levels, that relate to the prognosis. (C) 2000 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/04/20 alle ore 09:11:56