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Titolo:
Primary biliary cirrhosis: new perspectives in diagnosis and treatment
Autore:
Prince, MI; Jones, DEJ;
Indirizzi:
Univ Newcastle, Liver Res Ctr, Sch Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England Univ Newcastle Newcastle Upon Tyne Tyne & Wear England NE24HH r, England
Titolo Testata:
POSTGRADUATE MEDICAL JOURNAL
fascicolo: 894, volume: 76, anno: 2000,
pagine: 199 - 206
SICI:
0032-5473(200004)76:894<199:PBCNPI>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
URSODEOXYCHOLIC ACID THERAPY; PLACEBO-CONTROLLED TRIAL; SERUM BILE-ACIDS; DOUBLE-BLIND; ANTIMITOCHONDRIAL ANTIBODY; LIVER-TRANSPLANTATION; CLINICAL-FEATURES; MAYO MODEL; AUTOIMMUNE CHOLANGITIS; RETROVIRAL ANTIBODIES;
Keywords:
primary biliary cirrhosis; liver transplantation; pruritus;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
113
Recensione:
Indirizzi per estratti:
Indirizzo: Jones, DEJ Univ Newcastle, Liver Res Ctr, Sch Med, 4th Floor,William LeechBldg,Framlington Pl, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England Univ Newcastle 4th Floor,William Leech Bldg,Framlington Pl Newcastle Upon TyneTyne & Wear England NE2 4HH
Citazione:
M.I. Prince e D.E.J. Jones, "Primary biliary cirrhosis: new perspectives in diagnosis and treatment", POSTG MED J, 76(894), 2000, pp. 199-206

Abstract

Primary biliary cirrhosis (PBC) is a chronic autoimmune disease characterised by cholestatic liver function tests, antimitochondrial antibodies, and abnormal liver histology. Early descriptions of a rare rapidly progressive disease no longer reflect the more indolent progress often seen today. Manypatients have significant long term morbidity through symptoms such as fatigue and itch with a minority progressing to liver failure and need for transplantation. The current data on the diagnosis, clinical progression, and treatment of PBC are reviewed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 07:20:39