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Titolo:
Effect of lactic acid bacteria on diarrheal diseases
Autore:
Heyman, M;
Indirizzi:
Fac Necker, INSERM, CJF 9710, Natl Inst Hlth & Med Res, F-75730 Paris, France Fac Necker Paris France F-75730 st Hlth & Med Res, F-75730 Paris, France
Titolo Testata:
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
fascicolo: 2, volume: 19, anno: 2000, supplemento:, S
pagine: 137S - 146S
SICI:
0731-5724(200004)19:2<137S:EOLABO>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
TOXIGENIC ESCHERICHIA-COLI; CLOSTRIDIUM-DIFFICILE COLITIS; HUMAN LACTOBACILLUS STRAIN; GG PROMOTES RECOVERY; FERMENTED MILK; ROTAVIRUS GASTROENTERITIS; MALNOURISHED CHILDREN; PERSISTENT DIARRHEA; INTESTINAL FLORA; SUCKLING RATS;
Keywords:
intestinal function; diarrhea; lactic acid bacteria; bifidobacteria; probiotics;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
75
Recensione:
Indirizzi per estratti:
Indirizzo: Heyman, M Fac Necker, INSERM, CJF 9710, Natl Inst Hlth & Med Res, 156 Rue de Vaugirard, F-75730 Paris, France Fac Necker 156 Rue de Vaugirard Paris France F-75730 is, France
Citazione:
M. Heyman, "Effect of lactic acid bacteria on diarrheal diseases", J AM COL N, 19(2), 2000, pp. 137S-146S

Abstract

Microbial balance is an important factor in the maintenance of intestinal homeostasis, and yogurt or fermented milk supplementation has been proposedto control diarrheal diseases. A number of studies using animal models andclinical studies in humans have confirmed the beneficial effect of such fermented products in case of lactose intolerance, viral diarrhea or antibiotics-associated diarrhea. The mechanisms by which lactic acid bacteria exerttheir effects are multiple. Bacterial lactase improves the absorption of lactose, but fermented products slow down the intestinal transit facilitating the action of residual intestinal lactase. The transient passage of lactic acid bacteria in the digestive tract may represent a microbial barrier against the development of pathogenic bacteria, probably due to the release of compounds contributing to the maintenance of colonization resistance to pathogens. The beneficial effects are mainly described in the presence of Live bacteria, but inactivated bacteria may also present preventive or curative capacities in diarrheal diseases. Moreover, lactic acid bacteria has been described as reinforcing the non-specific immune defence but also specific immunity, particularly the secretory immune system mediated by secretory IgA or IgM in response to particulate infectious antigens and perhaps to soluble food antigens. Other possible mechanisms include the trophic effect on the intestinal layer, and a down-regulatory activity in cow's milk allergy as well as anti-inflammatory effects have also been suggested.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 16:18:14