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Titolo:
Glutamic acid, twenty years later
Autore:
Garattini, S;
Indirizzi:
Mario Negri Inst Pharmacol Res, I-20157 Milan, Italy Mario Negri Inst Pharmacol Res Milan Italy I-20157 I-20157 Milan, Italy
Titolo Testata:
JOURNAL OF NUTRITION
fascicolo: 4, volume: 130, anno: 2000, supplemento:, S
pagine: 901S - 909S
SICI:
0022-3166(200004)130:4<901S:GATYL>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
NMDA RECEPTOR ANTAGONIST; FOCAL CEREBRAL-ISCHEMIA; IN-VIVO MICRODIALYSIS; BLOOD-BRAIN-BARRIER; MONOSODIUM GLUTAMATE; GLYCINE SITE; EXTRACELLULAR GLUTAMATE; PYROGLUTAMIC ACID; NERVOUS-SYSTEM; RAT HIPPOCAMPUS;
Keywords:
glutamic acid; monosodium glutamate; metabolism; central nervous system; neurodegeneration; N-methyl-D-aspartate; alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate; metabotropic receptors; glutamate transporters;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
115
Recensione:
Indirizzi per estratti:
Indirizzo: Garattini, S Mario Negri Inst Pharmacol Res, Via Eritrea 62, I-20157 Milan, Italy Mario Negri Inst Pharmacol Res Via Eritrea 62 Milan Italy I-20157
Citazione:
S. Garattini, "Glutamic acid, twenty years later", J NUTR, 130(4), 2000, pp. 901S-909S

Abstract

This review examines progress in understanding the physiologic functions of glutamic acid in the body since the first symposium on glutamic acid physiology and biochemistry was held at the Mario Negri Institute in Milan in 1978. The topics reviewed, although not exhaustive, include the metabolism of glutamic acid, umami taste, the role of glutamic acid as a neurotransmitter, glutamate safety and the development of new drugs resulting from the knowledge of the neurodegeneration induced by high doses of glutamic acid.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 01:52:39