Catalogo Articoli (Spogli Riviste)

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Titolo:
Effect of age and Helicobacter pylori infection on gastric acid secretion
Autore:
Haruma, K; Kamada, T; Kawaguchi, H; Okamoto, S; Yoshihara, M; Sumii, K; Inoue, M; Kishimoto, S; Kajiyama, G; Miyoshi, A;
Indirizzi:
Hiroshima Univ, Sch Med, Dept Internal Med 1, Gastrointestinal Unit,MinamiKu, Hiroshima 7348551, Japan Hiroshima Univ Hiroshima Japan 7348551 inamiKu, Hiroshima 7348551, Japan
Titolo Testata:
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
fascicolo: 3, volume: 15, anno: 2000,
pagine: 277 - 283
SICI:
0815-9319(200003)15:3<277:EOAAHP>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
PEPTIC-ULCER DISEASE; DUODENAL-ULCER; SERUM GASTRIN; CAMPYLOBACTER-PYLORI; HEALTHY-SUBJECTS; SYDNEY SYSTEM; SEX; ERADICATION; DIAGNOSIS; JAPANESE;
Keywords:
age; atrophic gastritis; gastric acid secretion; Helicobacter pylori;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Haruma, K Hiroshima Univ, Sch Med, Dept Internal Med 1, Gastrointestinal Unit,MinamiKu, 1-2-3 Kasumi, Hiroshima 7348551, Japan Hiroshima Univ 1-2-3 Kasumi Hiroshima Japan 7348551 8551, Japan
Citazione:
K. Haruma et al., "Effect of age and Helicobacter pylori infection on gastric acid secretion", J GASTR HEP, 15(3), 2000, pp. 277-283

Abstract

Background: Whether gastric acid secretion decreases with age is still controversial. With the discovery of Helicobacter pylori, the association of this bacterium with gastric acid secretion has also been discussed. The aim of this study was to investigate the relationship between gastric acid secretion, age and H. pylori infection. Methods: The presence of H. pylori infection, the grade of fundic atrophicgastritis (FAG), and gastric acid secretion were investigated in 280 subjects without localized lesions in the upper gastrointestinal tract. Helicobacter pylori infection was confirmed by Giemsa and immunohistochemical staining, and FAG of biopsy specimens was graded on a scale of 0-4. Results: Both basal and maximal acid output decreased with age in H. pylori-positive subjects, while they did not change with age in H. pylori-negative subjects. Gastric acid secretion decreased with the progression of FAG. An age-correlated decrease in gastric acid secretion in H. pylori-positive subjects depended on an increasing prevalence of FAG with age. Conclusions: In the population studied, advancing age had no influence on gastric acid secretion in H. pylori-negative subjects. Gastric acid secretion decreases with age in H. pylori-positive subjects because of the increasing prevalence of FAG with age. (C) 2000 Blackwell Science Asia Pty Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 17:40:26