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Titolo:
Palmar and axillary hyperhidrosis treated with botulinum toxin: one-year clinical follow-up
Autore:
Naver, H; Swartling, C; Aquilonius, SM;
Indirizzi:
Univ Uppsala Hosp, Dept Neurol, SE-75185 Uppsala, Sweden Univ Uppsala Hosp Uppsala Sweden SE-75185 urol, SE-75185 Uppsala, Sweden Univ Uppsala Hosp, Dept Neurosci, SE-75185 Uppsala, Sweden Univ Uppsala Hosp Uppsala Sweden SE-75185 osci, SE-75185 Uppsala, Sweden Univ Uppsala Hosp, Dept Dermatol, SE-75185 Uppsala, Sweden Univ Uppsala Hosp Uppsala Sweden SE-75185 atol, SE-75185 Uppsala, Sweden
Titolo Testata:
EUROPEAN JOURNAL OF NEUROLOGY
fascicolo: 1, volume: 7, anno: 2000,
pagine: 55 - 62
SICI:
1351-5101(200001)7:1<55:PAAHTW>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOCAL HYPERHIDROSIS; ENDOSCOPIC SYMPATHECTOMY;
Keywords:
botulinum toxin; duration; hyperhidrosis; injection; intradermal; side-effects; sweat; therapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Naver, H Univ Uppsala Hosp, Dept Neurol, SE-75185 Uppsala, Sweden Univ Uppsala Hosp Uppsala Sweden SE-75185 75185 Uppsala, Sweden
Citazione:
H. Naver et al., "Palmar and axillary hyperhidrosis treated with botulinum toxin: one-year clinical follow-up", EUR J NEUR, 7(1), 2000, pp. 55-62

Abstract

Focal hyperhidrosis is a common and sometimes handicapping condition for which the presently most effective treatment, sympathectomy, often leads to irreversible side-effects. We aimed to study effectiveness and tolerabilityof an alternative treatment with botulinum toxin injections over a period of one year for this condition. Twenty-eight patients with palmar (n = 19) and/or axillary (n = 13) hyperhidrosis were treated with intracutaneous injections of botulinum toxin (Botox(R)) 2 U/4 cm(2). Sweat function was studied clinically and by objective measurements after treatment of one side. Treated and untreated sides, and pre- and post-treatment skin areas were compared. Subjective evaluation wasperformed after treatment of one side and 2-5 months after treatment of both sides. Duration of effect was controlled by a one-year follow-up. Sweating disappeared in eight out of 13 patients with axillary and in fiveout of 19 with palmar hyperhidrosis, and was reduced markedly in another five out of 13 and 10 out of 19 patients. Two-thirds of those treated for hand sweat noticed a slight and transient reduction of power of finger grip. No side-effects were noticed after treatment of axillary hyperhidrosis. We find intracutaneous injections of botulinum toxin with this technique safe and effective, and due to the relatively long duration of effect the treatment should be recommended before sympathectomy for focal hyperhidrosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 12:02:43