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Titolo:
Cardiac markers: Centralized or decentralized testing?
Autore:
Plebani, M; Zaninotto, M;
Indirizzi:
Univ Hosp Padova, Dept Lab Med, I-35128 Padua, Italy Univ Hosp Padova Padua Italy I-35128 Dept Lab Med, I-35128 Padua, Italy
Titolo Testata:
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
fascicolo: 11-12, volume: 37, anno: 1999,
pagine: 1113 - 1117
SICI:
1434-6621(199911/12)37:11-12<1113:CMCODT>2.0.ZU;2-
Fonte:
ISI
Lingua:
ENG
Soggetto:
MYOCARDIAL-INFARCTION; EMERGENCY;
Keywords:
acute myocardial infarction; acute coronary syndromes; near-patient testing; cardiac troponins; myoglobin; CK-MB;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Plebani, M Univ Hosp Padova, Dept Lab Med, Via Giustiniani 2, I-35128 Padua, Italy Univ Hosp Padova Via Giustiniani 2 Padua Italy I-35128 , Italy
Citazione:
M. Plebani e M. Zaninotto, "Cardiac markers: Centralized or decentralized testing?", CLIN CH L M, 37(11-12), 1999, pp. 1113-1117

Abstract

Testing for the diagnosis of acute myocardial infarction and other diseases included in the spectrum of the "acute coronary syndrome" is rapidly changing from the traditional enzymatic assays to mass measurement bf more specific and sensitive markers (cardiac troponins, CK-MB and myoglobin). Several questions have arisen since the introduction of these new markers into the clinical setting: the choice of strategies for optimizing the utilizationof biochemical assays combining different (early and specific) markers, a rationale for sampling specimens and the identification of clinically useful turnaround times. In particular, for achieving the last goal, attention has been directed toward near-patient testing for cardiac markers in addition to, or as a replacement for, traditional diagnostic methodologies. While qualitative methods for measuring cardiac markers at the bedside have some limitations which compromise their clinical usefulness, new quantitative devices offer a real alternative to decentralized testing. Regulatory and quality management issues related to near-patient testing, as well as the performance of recently introduced devices for a decentralized measurement of cardiac markers are reviewed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 04:53:05