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Titolo:
NEOPLASIA IN ILEAL POUCH MUCOSA AFTER TOTAL PROCTOCOLECTOMY FOR JUVENILE POLYPOSIS - REPORT OF A CASE
Autore:
STOLTENBERG RL; MADSEN JA; SCHLACK SC; HARMS BA; JACOBY RF;
Indirizzi:
UNIV WISCONSIN,SCH MED,DEPT SURG,600 HIGHLAND AVE H6-516 MADISON WI 53792 UNIV WISCONSIN,SCH MED,DEPT SURG MADISON WI 53792 UNIV WISCONSIN,DEPT PATHOL MADISON WI 53792 UNIV WISCONSIN,DEPT MED,GASTROENTEROL SECT MADISON WI 53792 UNIV WISCONSIN,CTR COMPREHENS CANC MADISON WI 53706 WILLIAM S MIDDLETON MEM VET ADM MED CTR MADISON WI 00000
Titolo Testata:
Diseases of the colon & rectum
fascicolo: 6, volume: 40, anno: 1997,
pagine: 726 - 730
SICI:
0012-3706(1997)40:6<726:NIIPMA>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
ILEOANAL ANASTOMOSIS; ULCERATIVE-COLITIS; FAMILIAL POLYPOSIS; TOTAL COLECTOMY; CARCINOMA; PATHOGENESIS; RISK;
Keywords:
PROCTOCOLECTOMY, RESTORATIVE; NEOPLASTIC SYNDROMES, HEREDITARY; INTESTINAL POLYPS; COLONIC POLYPS; ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
R.L. Stoltenberg et al., "NEOPLASIA IN ILEAL POUCH MUCOSA AFTER TOTAL PROCTOCOLECTOMY FOR JUVENILE POLYPOSIS - REPORT OF A CASE", Diseases of the colon & rectum, 40(6), 1997, pp. 726-730

Abstract

PURPOSE: Patients treated with restorative proctocolectomy for familial adenomatous polyposis or ulcerative colitis occasionally develop disease in the ileal pouch similar to that originally present in the colon. We investigated the possibility of analogous involvement in the ileal pouch of juvenile polyposis patients. METHODS: Endoscopic surveillance for neoplasia throughout the gastrointestinal tract was performed, with retrieval of all polypectomy specimens for histologic classification using the criteria of Morson. RESULTS: Multiple large juvenile polyps were found in the ileal pouch of one patient less than 10 years after restorative proctocolectomy for hereditary juvenile polyposis. The pouch was much more severely affected than the proximal ileum, small intestine, or stomach. Although most polyps had a completely benign histologic appearance, three had moderate to severe dysplasia. DISCUSSION: Mucosal changes induced by bacteria or stasis of luminal contentsmay promote manifestation in the ileal pouch of the disease phenotypeusually more evident in the colon. Patients with severe or generalized juvenile polyposis should be considered for periodic endoscopic surveillance of the ileal pouch beginning several years after restorative proctocolectomy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 15:40:59