Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Serum homocyst(e)ine levels in women with preeclampsia
Autore:
Mayerhofer, K; Hefler, L; Zeisler, H; Tempfer, C; Bodner, K; Stockler-Ipsiroglu, S; Muhl, A; Kaider, A; Schatten, C; Leodolter, S; Husslein, P; Kainz, C;
Indirizzi:
Univ Vienna, Sch Med, Dept Gynecol, Vienna, Austria Univ Vienna Vienna Austria enna, Sch Med, Dept Gynecol, Vienna, Austria Univ Vienna, Sch Med, Dept Obstet, Vienna, Austria Univ Vienna Vienna Austria ienna, Sch Med, Dept Obstet, Vienna, Austria Univ Vienna, Sch Med, Dept Pediat, Vienna, Austria Univ Vienna Vienna Austria ienna, Sch Med, Dept Pediat, Vienna, Austria Univ Vienna, Sch Med, Dept Med Comp Sci Biometr, Vienna, Austria Univ Vienna Vienna Austria , Dept Med Comp Sci Biometr, Vienna, Austria Baylor Coll Med, Dept Obstet & Gynecol, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 tet & Gynecol, Houston, TX 77030 USA
Titolo Testata:
WIENER KLINISCHE WOCHENSCHRIFT
fascicolo: 6, volume: 112, anno: 2000,
pagine: 271 - 275
SICI:
0043-5325(20000324)112:6<271:SHLIWW>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
RISK FACTOR; HYPERHOMOCYSTEINEMIA; HOMOCYSTEINE; HOMOCYSTINURIA; PREGNANCIES; DEFICIENCY;
Keywords:
homocyst(e)ine; preeclampsia; pregnancy; prognosis; serum;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Mayerhofer, K Univ Vienna, Sch Med, Dept Gynecol & Obstet, Wahringer Gurtel 18-20, A-1090 Vienna, Austria Univ Vienna Wahringer Gurtel 18-20 Vienna Austria A-1090 ia
Citazione:
K. Mayerhofer et al., "Serum homocyst(e)ine levels in women with preeclampsia", WIEN KLIN W, 112(6), 2000, pp. 271-275

Abstract

Background: Endothelial dysfunction has been described as the final commonpathophysiological pathway in the development of preeclampsia. Since it has been suggested that homocyst(e)ine damages endothelial cells, we measuredserum homocyst(e)ine levels in women with preeclampsia and in healthy pregnant women in order to find a new prognostic parameter for women with preeclampsia. Methods. Forty-five women with preeclampsia and 45 healthy women with uncomplicated pregnancies, matched for age and parity, were entered into the study. Serum homocyst(e)ine levels were measured by gas chromatography-mass spectrometry analysis and correlated to clinical data. Logistic regression models were used to analyse the influence of serum homocyst(e)ine levels on the presence of preeclampsia versus healthy pregnant women and on the risk of premature termination of pregnancy due to preeclampsia. Results: Median serum homocyst(e)ine levels in women with preeclampsia andhealthy pregnant women were 14.2 (range 5.7-38.1) mu mol/L and 15.1 (range5.2-23.1) mu mol/L, respectively (Mann-Whitney U-test, p = 0.8). In univariate logistic regression models, serum homocyst(e)ine levels had no significant influence on the odds of presenting with preeclampsia versus healthy pregnant women (univariate logistic regression model, p = 0.8) and on the odds of premature termination of pregnancy due to preeclampsia (univariate logistic regression model, p = 0.3). Conclusions: Serum homocyst(e)ine levels are not elevated in women with preeclampsia and are not associated with clinical outcome in women with preeclampsia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 06:24:56