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Titolo:
Harmonic hepatic US with microbubble contrast agent: Initial experience showing improved characterization of hemangioma, hepatocellular carcinoma,andmetastasis
Autore:
Wilson, SR; Burns, PN; Muradali, D; Wilson, JA; Lai, XM;
Indirizzi:
Toronto Gen Hosp, Dept Med Imaging, Toronto, ON M5G 2C4, Canada Toronto Gen Hosp Toronto ON Canada M5G 2C4 g, Toronto, ON M5G 2C4, Canada
Titolo Testata:
RADIOLOGY
fascicolo: 1, volume: 215, anno: 2000,
pagine: 153 - 161
SICI:
0033-8419(200004)215:1<153:HHUWMC>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
DOPPLER; LIVER; ULTRASOUND; ALBUMIN;
Keywords:
liver, US; liver neoplasms; liver neoplasms, US; microbubbles; ultrasound (US), contrast media; ultrasound (US), harmonic study;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Wilson, SR Toronto Gen Hosp, Dept Med Imaging, 200 Elizabeth St, Toronto, ON M5G 2C4,Canada Toronto Gen Hosp 200 Elizabeth St Toronto ON Canada M5G 2C4 ada
Citazione:
S.R. Wilson et al., "Harmonic hepatic US with microbubble contrast agent: Initial experience showing improved characterization of hemangioma, hepatocellular carcinoma,andmetastasis", RADIOLOGY, 215(1), 2000, pp. 153-161

Abstract

PURPOSE: To characterize blood flow in focal hepatic lesions with harmonicultrasonographic (US) imaging and a microbubble contrast agent. MATERIALS AND METHODS: Thirty patients with known hepatic masses were examined after injection of a perfluorocarbon microbubble agent. Tumor vascularity was assessed with continuous, harmonic gray-scale imaging with a low mechanical index (MI). Tumor vascular volume was assessed with brief, high-MIinsonation called interval-delay imaging, which caused microbubble destruction. As the total contrast agent volume in the liver reflects the total vascular volume, quantitation of lesion enhancement relative to normal hepatic enhancement helped determine the vascular volume of the tumor relative tothat of normal parenchyma. RESULTS: Low-MI continuous harmonic imaging showed lesional vessels in hepatocellular carcinomas, minimal or no vessels in hemangiomas, and variable vascularization in metastases. High-MI interval-delay imaging showed greater enhancement in hepatocellular carcinomas than in normal liver (P < .02) and showed less enhancement in hemangiomas than in normal liver (P < .02). Enhancement in metastases was greater in the margins than in the center; as a result, the lesions appeared smaller (P < .03) and less well defined on the interval-delay images. CONCLUSION: Contrast-enhanced harmonic imaging appears superior to conventional Doppler US for hepatic mass characterization. Low-MI continuous and high-M I interval-delay imaging can help assess tu mor vascular pattern and microvascular volume.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/08/20 alle ore 23:25:06