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Titolo:
Detection of Epstein-Barr virus in salivas and throat washings in healthy adults and children
Autore:
Ikuta, K; Satoh, Y; Hoshikawa, Y; Sairenji, T;
Indirizzi:
Tottori Univ, Fac Med, Sch Life Sci, Dept Biosignaling, Yonago, Tottori 6838503, Japan Tottori Univ Yonago Tottori Japan 6838503 Yonago, Tottori 6838503, Japan
Titolo Testata:
MICROBES AND INFECTION
fascicolo: 2, volume: 2, anno: 2000,
pagine: 115 - 120
SICI:
1286-4579(200002)2:2<115:DOEVIS>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
POLYMERASE CHAIN-REACTION; ACUTE INFECTIOUS-MONONUCLEOSIS; GASTRIC-CARCINOMA; EPITHELIAL-CELLS; DNA; REPLICATION; OROPHARYNX; INVITRO; STRAIN;
Keywords:
EBV; EBV detection by PCR; EBV in saliva;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Sairenji, T Tottori Univ, Fac Med, Sch Life Sci, Dept Biosignaling, Yonago, Tottori 6838503, Japan Tottori Univ Yonago Tottori Japan 6838503 tori 6838503, Japan
Citazione:
K. Ikuta et al., "Detection of Epstein-Barr virus in salivas and throat washings in healthy adults and children", MICROBES IN, 2(2), 2000, pp. 115-120

Abstract

It is well known that Epstein-Barr virus (EBV) is excreted from oral regions in the patients with infectious mononucleosis. We analyzed the prevalence of EBV in saliva and throat washings from healthy people in Japan by the polymerase chain reaction assay. EBV DNA was detected in 43 (90%) of the 48throat washings from healthy adults (21 to 57 years old) and in 35 (38%) of the 93 salivas from healthy children (0 to 6 years old). The percentages of the EBV DNA-positive ratio in salivas increased in proportion relative to the increase of the children's ages. EBV type 1 was predominant and was detected in 86 and 94% of adults and children, respectively. Umbilical cord lymphocytes were transformed by some throat washings from EBV seropositive donors. EBV DNA was detected in throat washings from two healthy adults whose EBV antibody was not detected. In both cases, higher amounts of EBV DNA were detected in their peripheral blood mononuclear cells than in those of other, EBV antibody-positive donors. These results demonstrated the incidence of EBV excretion in oral regions of healthy individuals in Japan and defined a novel type of EBV infection in healthy adults. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 09:53:01