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Titolo:
Divergent evolution of plant NBS-LRR resistance gene homologues in dicot and cereal genomes
Autore:
Pan, QL; Wendel, J; Fluhr, R;
Indirizzi:
Weizmann Inst Sci, Dept Plant Sci, IL-76100 Rehovot, Israel Weizmann Inst Sci Rehovot Israel IL-76100 Sci, IL-76100 Rehovot, Israel Iowa State Univ, Dept Bot, Ames, IA 50011 USA Iowa State Univ Ames IA USA50011 tate Univ, Dept Bot, Ames, IA 50011 USA
Titolo Testata:
JOURNAL OF MOLECULAR EVOLUTION
fascicolo: 3, volume: 50, anno: 2000,
pagine: 203 - 213
SICI:
0022-2844(200003)50:3<203:DEOPNR>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
DOWNY MILDEW RESISTANCE; NUCLEOTIDE-BINDING SITE; FLAX RUST RESISTANCE; RICH REPEAT CLASS; MAP-BASED CLONING; DISEASE-RESISTANCE; ARABIDOPSIS-THALIANA; CLADOSPORIUM-FULVUM; DROSOPHILA TOLL; TOMATO;
Keywords:
plant disease resistance genes; innate immunity; evolution;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
50
Recensione:
Indirizzi per estratti:
Indirizzo: Fluhr, R Weizmann Inst Sci, Dept Plant Sci, POB 26, IL-76100 Rehovot, Israel Weizmann Inst Sci POB 26 Rehovot Israel IL-76100 Rehovot, Israel
Citazione:
Q.L. Pan et al., "Divergent evolution of plant NBS-LRR resistance gene homologues in dicot and cereal genomes", J MOL EVOL, 50(3), 2000, pp. 203-213

Abstract

The majority of plant disease resistance genes are members of very large multigene families. They encode structurally related proteins containing nucleotide binding site domains (NBS) and C-terminal leucine rich repeats (LRR). The N-terminal region of some resistance genes contain a short sequence called TIR with homology to the animal innate immunity factors, Toll and interleukin receptor-like genes. Only a few plant resistance genes have been functionally analyzed and the origin and evolution of plant resistance genes remain obscure. We have reconstructed gene phylogeny by exhaustive analysis of available genome and amplified NBS domain sequences. Our study shows that NBS domains faithfully predict whole gene structure and can be dividedinto two major groups. Group I NBS domains contain group-specific motifs that are always linked with the TIR sequence in the N terminus. Significantly, Group I NBS domains and their associated TIR domains are widely distributed in dicot species but were not detected in cereal databases. Furthermore, Group I specific NBS sequences were readily amplified from dicot genomic DNA but could not be amplified from cereal genomic DNA. In contrast, Group II NBS domains are always associated with putative coiled-coil domains in their N terminus and appear to be present throughout the angiosperms. These results suggest that the two main groups of resistance genes underwent divergent evolution in cereal and dicot genomes and imply that their cognate signaling pathways have diverged as well.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 20:35:43