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Titolo:
A comprehensive model of the development of mental handicap in children treated for acute lymphoblastic leukaemia: A synthesis of the literature
Autore:
Robaey, P; Dobkin, P; Leclerc, JM; Cyr, F; Sauerwein, C; Theoret, Y;
Indirizzi:
Hop St Justine, Ctr Rech, Montreal, PQ H3T 1C5, Canada Hop St Justine Montreal PQ Canada H3T 1C5 h, Montreal, PQ H3T 1C5, Canada McGill Univ, Montreal, PQ, Canada McGill Univ Montreal PQ CanadaMcGill Univ, Montreal, PQ, Canada Montreal Gen Hosp, Montreal, PQ H3G 1A4, Canada Montreal Gen Hosp Montreal PQ Canada H3G 1A4 Montreal, PQ H3G 1A4, Canada Univ Montreal, Montreal, PQ, Canada Univ Montreal Montreal PQ CanadaUniv Montreal, Montreal, PQ, Canada
Titolo Testata:
INTERNATIONAL JOURNAL OF BEHAVIORAL DEVELOPMENT
fascicolo: 1, volume: 24, anno: 2000,
pagine: 44 - 58
SICI:
0165-0254(200003)24:1<44:ACMOTD>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL-NERVOUS-SYSTEM; LONG-TERM SURVIVORS; ACUTE LYMPHOCYTIC-LEUKEMIA; BLOOD-BRAIN-BARRIER; CANCER-STUDY-GROUP; POSITRON EMISSION TOMOGRAPHY; KILLS POSTMITOTIC NEURONS; CGY CRANIAL IRRADIATION; CHILDHOOD LEUKEMIA; PSYCHOLOGICAL ADJUSTMENT;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
159
Recensione:
Indirizzi per estratti:
Indirizzo: Robaey, P Dept Psychiat, Lab Psychophysiol Cognit & Neuropsychiat, 3100 Ellendale, Montreal, PQ H3S 1W3, Canada Dept Psychiat 3100 Ellendale MontrealPQ Canada H3S 1W3 , Canada
Citazione:
P. Robaey et al., "A comprehensive model of the development of mental handicap in children treated for acute lymphoblastic leukaemia: A synthesis of the literature", INT J BEHAV, 24(1), 2000, pp. 44-58

Abstract

Most clinical studies addressing sequelae in children with leukaemia are not theory-driven, Nonetheless, the role of different mediating biological (e.g, cranial irradiation, chemotherapy) and psychosocial variables (e.g. family functioning) has been empirically acknowledge. In these studies, a cause-effect relationship between biological variables and cognitive deficits,sometimes complex due to multiple agents, has been hypothesised. As for the psychosocial consequences, adaptation to the cancer-related stress has been the main focus, at both the individual and family levels. In this paper,we advocate the use of a global model for the development of handicap, derived from the International Classification of Impairments, Disabilities andHandicaps (ICIDH) by the World Health Organisation. This revised model proposes that handicap is the result of complex interactions between the characteristics of a person's impairment, disabilities, and the characteristics of the environment. At each of these levels? risk/resilience factors are defined. This means that depending on the environmental obstacles they face, persons with an impairment or a disability may or may not experience a situation creating a handicap which is no longer seen as a stable status resulting from a disease to which the individual must adapt. By reviewing animal and clinical studies, current knowledge pertaining to leukaemia sequelae are integrated into the different levels defined by the model: organic impairment, disabilities, environmental obstacles, and handicap situation. Practical implications for research, policies, and individual treatments, and comparisons with existing models, are also outlined.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 18:27:35