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Titolo:
Influence of monaural deprivation on the development of the auditory brainstem in the Mongolian gerbil (Meriones unguiculatus)
Autore:
Ernst, S; Foerst, A; Hessel, H; Klunter, HD; von Wedel, H; Walkowiak, W; Walger, M;
Indirizzi:
Univ Cologne, Klin & Poliklin Hals Nasen & Ohrenheilkunde, D-50924 Cologne, Germany Univ Cologne Cologne Germany D-50924 heilkunde, D-50924 Cologne, Germany
Titolo Testata:
HNO
fascicolo: 3, volume: 48, anno: 2000,
pagine: 195 - 203
SICI:
0017-6192(200003)48:3<195:IOMDOT>2.0.ZU;2-#
Fonte:
ISI
Lingua:
GER
Soggetto:
ANTEROVENTRAL COCHLEAR NUCLEUS; CONDUCTIVE HEARING-LOSS; EVOKED-POTENTIALS; GUINEA-PIGS; NEURONS; RAT; COMPONENTS; MATURATION; REMOVAL;
Keywords:
auditory deprivation; ABR; development; sensitive period; plasticity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Ernst, S Univ Cologne, Klin & Poliklin Hals Nasen & Ohrenheilkunde, JosephStelzmann Str 9, D-50924 Cologne, Germany Univ Cologne Joseph Stelzmann Str 9 Cologne Germany D-50924 many
Citazione:
S. Ernst et al., "Influence of monaural deprivation on the development of the auditory brainstem in the Mongolian gerbil (Meriones unguiculatus)", HNO, 48(3), 2000, pp. 195-203

Abstract

Several investigations prove that monaural acoustic deprivation induces detrimental changes in the auditory pathway. So far the major interest focused on degenerative processes on the deprived side,while effects on the contralateral untreated side were not taken into consideration. This ontogeneticstudy investigates effects of early monaural acoustic deprivation on the functional development of the acoustically evoked auditory brainstem response (ABR) in the Mongolian gerbil. Young gerbils were deafened by a single intracochlear application of neomycin sulfate. The ABR development on the contralateral side differed in a late developmental period from that of normally hearing animals. These changes persisted until adulthood. Between day 55and day 90 a significant 5 dB decrease of the ABR thresholds and a significant shortening of the interpeak latency Il-V occured. The results confirm that a complete monaural deprivation during the sensible or critical periodleads on the contralateral side to plastic or compensatory changes in the auditory brainstem.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/11/20 alle ore 20:25:16