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Titolo:
Age- and gender-specific differences in left and right ventricular cardiacfunction and mass determined by cine magnetic resonance imaging
Autore:
Sandstede, J; Lipke, C; Beer, M; Hofmann, S; Pabst, T; Kenn, W; Neubauer, S; Hahn, D;
Indirizzi:
Univ Wurzburg, Inst Rontgendiagnost, D-97080 Wurzburg, Germany Univ Wurzburg Wurzburg Germany D-97080 agnost, D-97080 Wurzburg, Germany Univ Wurzburg, Med Klin, D-97080 Wurzburg, Germany Univ Wurzburg Wurzburg Germany D-97080 d Klin, D-97080 Wurzburg, Germany
Titolo Testata:
EUROPEAN RADIOLOGY
fascicolo: 3, volume: 10, anno: 2000,
pagine: 438 - 442
SICI:
0938-7994(2000)10:3<438:AAGDIL>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYSTOLIC FUNCTION; NORMAL ADULTS; QUANTIFICATION; VOLUMES;
Keywords:
heart; magnetic resonance imaging; heart function tests; cardiac volume;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Sandstede, J Univ Wurzburg, Inst Rontgendiagnost, Josef Schneider Str 2, D-97080 Wurzburg, Germany Univ Wurzburg Josef Schneider Str 2 Wurzburg Germany D-97080
Citazione:
J. Sandstede et al., "Age- and gender-specific differences in left and right ventricular cardiacfunction and mass determined by cine magnetic resonance imaging", EUR RADIOL, 10(3), 2000, pp. 438-442

Abstract

We examined possible age- and gender-specific differences in the function and mass of left (LV) and right (RV) and right (RV) ventricles in 36 healthy volunteers using cine gradient-recalled echo magnetic resonance imaging. Subjects were divided into four groups,(nine men and nine women in each): men aged under 45 years (32 +/- 7), women aged under 45 (27 +/- 6), men agedover 45 (59 +/- 8), and women aged over 45 (53 +/- 9). Functional analysisof cardiac volume and mass and of LV wall motion was performed by manu,al segmentation of the endocardial and epicardial borders of the end-diastolicand end-systolic frame; both absolute and normalized (per square meter body surface area) values were evaluated. With age,there was a significant decrease in both absolute and normalized LV and RV chamber volumes (EDV, ESV),while LV and RV masses remained unchanged. Gender-specific differences were found in cardiac mass and volume (for men and women, respectively: LV mass, 155 +/- 18 and 110 +/- 16 g; LV EDV, 118 +/- 27 I and 96 +/- 21 mi; LV ESV, 40 +/- 13 and 29 +/- 9 mi; RV mass, 52 +/- 10 and 39 +/- 5 g; RV EDV, 131 +/- 28 and 100 +/- 23 mi; RV ESV 53 +/- 17 and 33 +/- 15 mt). Nor: malization to body surface area eliminated differences es in LV volumes but not those in LV mass, RV mass, or RV function. Functional parameters such as cardiac output and LV ejection fraction showed nonsignificant or only slight differences and were thus largely independent of age and gender. Intra- andinterobserver variability ranged between 1.4% and 5.9% ;for all parameters. Cine magnetic resonance imaging thus shows age- and gender-specific differences in cardiac function, and therefore the evaluation of cardiac function in patients should consider age- and; gender-matched normative values.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 23:31:35