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Titolo:
Proposed abdominal sonographic staging to predict severity of liver diseases - Analysis with peritoneoscopy and histology
Autore:
Khan, KN; Yamasaki, M; Yamasaki, K; Inoue, O; Yatsuhashi, H; Koga, M; Yano, M;
Indirizzi:
Nagasaki Chuo Natl Hosp, WHO, Collaborating Ctr Reference & Res Viral Hepatitis, Inst Clin Res, Nagasaki 856, Japan Nagasaki Chuo Natl Hosp Nagasaki Japan 856 Clin Res, Nagasaki 856, Japan
Titolo Testata:
DIGESTIVE DISEASES AND SCIENCES
fascicolo: 3, volume: 45, anno: 2000,
pagine: 554 - 564
SICI:
0163-2116(200003)45:3<554:PASSTP>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
ETHANOL INJECTION THERAPY; HEPATOCELLULAR-CARCINOMA; LAPAROSCOPIC ULTRASONOGRAPHY; TEXTURE ANALYSIS; CHRONIC HEPATITIS; SJOGREN SYNDROME; PAROTID-GLAND; CLASSIFICATION; DIAGNOSIS; PROGNOSIS;
Keywords:
abdominal sonography; peritoneoscopy; histology; liver diseases; histogram-based standard deviation value;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Yatsuhashi, H Nagasaki Chuo Natl Hosp, WHO, Collaborating Ctr Reference & Res Viral Hepatitis, Inst Clin Res, 2-1001-1 Kubara, Nagasaki 856, Japan Nagasaki Chuo Natl Hosp 2-1001-1 Kubara Nagasaki Japan 856
Citazione:
K.N. Khan et al., "Proposed abdominal sonographic staging to predict severity of liver diseases - Analysis with peritoneoscopy and histology", DIG DIS SCI, 45(3), 2000, pp. 554-564

Abstract

Abdominal sonography is a routinely used noninvasive modality for screening and treatment of liver diseases. We attempted to establish a morphological sonographic staging to predict the severity of liver diseases with their consequent analysis with morphological staging of peritoneoscopy and histology. In all, 136 patients were enrolled for the final confirmation of disease state by peritoneoscopy and histology preceded by abdominal sonography. All patients were categorized from stage 0 to stage,5, depending on a proposed criterion of sonographic features based on surface pattern of liver andthe appearance of internal echogenic bands relating to the irregularity ofthe liver texture. A digitized computer quantitation of histogram-based standard deviation (sn) values from different stages of sonographic images was analyzed, and their values were justified by correlation with the definite appearance of an internal echogenic band. The association of different sonographic stages with disease progression was also demonstrated by their relation with peritoneoscopy and histology. In all patients, the different sonographic staging results were significantly correlated with hepatic surface features of peritoneoscopic staging (r = 0.939, P < 0.0001) graded from stage 0 to stage 5 and were also correlated with biopsy-proven staging of fibrosis (r = 0.739, P < 0.0001). The greater so values of histogram-based echo levels, as analyzed from digitized sonographic images of 90 patients, were associated with the appearance of internal echogenic bands (P < 0.0001). Furthermore, the corresponding sos were significantly correlated with the qualitative staging of sonographic features (r = 0.781, P < 0.0001), peritoneoscopy (r = 0.786, P < 0.0001) and histology (r = 0.779, P < 0.0001). We concluded that our proposed sonographic staging is well correlated with peritoneoscopic and histological staging of liver diseases, with only a small discrepancy, and can be used clinically to demonstrate the ongoing severityof liver diseases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 19:20:34