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Titolo:
Physiologically guided angioplasty in support to a provisional stenting strategy: Immediate and six-month outcome
Autore:
Dupouy, P; Pelle, G; Garot, P; Kern, MJ; Kane, G; Woscoboinick, J; Aptecar, E; Belarbi, A; Pernes, JM; Rande, JLD; Teiger, E;
Indirizzi:
Hop Henri Mondor, Serv Physiol & Explorat Fonct, Federat Cardiol, Unite Hemodynam & Cardiol Intervent,AP,HP, F-94010 Creteil, France Hop Henri Mondor Creteil France F-94010 t,AP,HP, F-94010 Creteil, France St Louis Univ, Hlth Sci Ctr, Div Cardiol, St Louis, MO 63103 USA St Louis Univ St Louis MO USA 63103 , Div Cardiol, St Louis, MO 63103 USA
Titolo Testata:
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
fascicolo: 4, volume: 49, anno: 2000,
pagine: 369 - 375
SICI:
1522-1946(200004)49:4<369:PGAIST>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY FLOW RESERVE; BALLOON ANGIOPLASTY; ARTERY DISEASE; VELOCITY-MEASUREMENTS; BLOOD-FLOW; RESTENOSIS; PRESSURE; TRIAL; INTERVENTIONS; ANGIOGRAPHY;
Keywords:
angioplasty; stent; restenosis; coronary velocity reserve; intracoronary Doppler;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Dupouy, P Hop Henri Mondor, Serv Physiol & Explorat Fonct, Federat Cardiol, Unite Hemodynam & Cardiol Intervent,AP,HP, F-94010 Creteil, France Hop Henri Mondor Creteil France F-94010 -94010 Creteil, France
Citazione:
P. Dupouy et al., "Physiologically guided angioplasty in support to a provisional stenting strategy: Immediate and six-month outcome", CATHET C IN, 49(4), 2000, pp. 369-375

Abstract

The results of an observational multicenter angioplasty study suggested that stenting decisions may be facilitated by physiologic data. The purpose of this study was to evaluate the early and long-term clinical and angiographic outcome of prospective physiologically guided provisional stenting. Coronary angioplasty using a Doppler-tipped angioplasty guidewire was performed in 68 patients. The provisional stent strategy dictated that balloon angioplasty was to be continued until a coronary flow reserve was greater than or equal to 2.2 with a residual diameter stenosis by quantitative coronary angiography < 35%. Repeat coronary angiography was obtained at 6 months. Based on the study criteria, 32/68 patients (47%) received a stent. Compared to the stent group, the angioplasty alone group had higher postprocedural stenosis (23% +/- 13% vs. 13% +/- 10%; P < 0.05) and lower coronary vasodilatory reserve (2.3 +/- 0.4 vs. 2.6 +/- 0.7; P < 0.05). At follow-up (6.0 +/-1.5 months), the angiographic restenosis rate was 39% in the angioplasty group and 35% in the stent groups (P = NS). Adverse cardiac events (unstableangina, target lesion revascularization, myocardial infarction, death) occurred in 19% and 18% (P = NS) of the angioplasty and stent patients, respectively. A prospective application of a physiologically guided provisional stent strategy for coronary angioplasty indicated that stent implantation may be required in approximately 50% of patients, an approach that produces similar clinical and angiographic long-term outcomes for stenting and guidedangioplasty. These data support a role of coronary physiology as an adjunct in conducting an angioplasty procedure without obligatory stenting. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 12:10:35