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Titolo:
Molecular cloning and sequencing of the cDNA encoding the feline Fc gamma RIIIA (CD16) homologue
Autore:
Nishimura, Y; Miyazawa, T; Ikeda, Y; Izumiya, Y; Nakamura, K; Sato, E; Mikami, T; Takahashi, E;
Indirizzi:
Univ Tokyo, Grad Sch Agr & Life Sci, Dept Vet Microbiol, Bunkyo Ku, Tokyo 1138657, Japan Univ Tokyo Tokyo Japan 1138657 icrobiol, Bunkyo Ku, Tokyo 1138657, Japan Obihiro Univ, Res Ctr Protozoan Mol Immunol, Obihiro, Hokkaido 0808555, Japan Obihiro Univ Obihiro Hokkaido Japan 0808555 hiro, Hokkaido 0808555, Japan
Titolo Testata:
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
fascicolo: 3-4, volume: 73, anno: 2000,
pagine: 353 - 359
SICI:
0165-2427(20000315)73:3-4<353:MCASOT>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
NATURAL-KILLER-CELLS; RECEPTOR; HETEROGENEITY; NEUTROPHILS; EXPRESSION;
Keywords:
cat; CD16; cDNA; cloning; Fc gamma RIII;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Takahashi, E Univ Tokyo, Grad Sch Agr & Life Sci, Dept Vet Microbiol, Bunkyo Ku, 1-1-1 Yayoi, Tokyo 1138657, Japan Univ Tokyo 1-1-1 Yayoi Tokyo Japan 1138657 yo 1138657, Japan
Citazione:
Y. Nishimura et al., "Molecular cloning and sequencing of the cDNA encoding the feline Fc gamma RIIIA (CD16) homologue", VET IMMUNOL, 73(3-4), 2000, pp. 353-359

Abstract

We amplified the cDNA encoding the feline Fc gamma RIIIA (CD16) homologue from peripheral blood mononuclear cells by polymerase chain reaction and cloned two forms of FCGR3A cDNA. Sequencing analysis revealed that the open reading frame of feline FCGR3A cDNA consists of 750 or 747 base pairs encoding 250 or 249 amino acid residues, respectively. Comparison of the predicted amino acid sequence of feline FCGR3A cDNA with those of other mammalians'homologues revealed that the extracellular domain has a relatively low homology. However, the cytoplasmic domain contained an 8-amino acid motif, Leu-Phe-Val-Val-Asp-Thr-Gly-Leu; which was considered to interact with an accessory molecule such as the gamma chain of Fc receptors for IgE to form heterodimeric complexes. (C) 2000 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 23:02:50