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Titolo:
Genetic amniocentesis in women 20-34 years old: associated risks
Autore:
Antsaklis, A; Papantoniou, N; Xygakis, A; Mesogitis, S; Tzortzis, E; Michalas, S;
Indirizzi:
Univ Athens, Dept Obstet & Gynecol 1, Maternal Fetal Med Unit, GR-10679 Athens, Greece Univ Athens Athens Greece GR-10679 tal Med Unit, GR-10679 Athens, Greece
Titolo Testata:
PRENATAL DIAGNOSIS
fascicolo: 3, volume: 20, anno: 2000,
pagine: 247 - 250
SICI:
0197-3851(200003)20:3<247:GAIW2Y>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRIAL;
Keywords:
amniocentesis; women aged 20-34 years; fetal loss; predisposing risk factors;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
6
Recensione:
Indirizzi per estratti:
Indirizzo: Antsaklis, A 11 Lampsakou Str, Athens 11528, Greece 11 Lampsakou Str Athens Greece 11528 , Athens 11528, Greece
Citazione:
A. Antsaklis et al., "Genetic amniocentesis in women 20-34 years old: associated risks", PRENAT DIAG, 20(3), 2000, pp. 247-250

Abstract

The aim of this retrospective controlled study is to evaluate the impact of predisposing factors on amniocentesis-related fetal loss. It comprises 3910 consecutive cases of women, aged 20-34 years, who had genetic amniocentesis during the years 1992-97 (study group). The control group comprised 5324 women under 35, at low risk for Down syndrome, during the same period. The fetal losses in both groups were analysed, in respect of: (a) maternal historical conditions; and/or (b) bleeding during current pregnancy. The leading indication for amniocentesis in women 20-34 years was maternal anxiety,mainly for marginal age (33-34 years), which accounted for a remarkable 34.4% of the study group. Total fetal loss rate up to the 28th week was 2.1% in the study group versus 1.5% in controls. A history of previous spontaneous or induced abortions, as well as bleeding during the current pregnancy, was associated with a substantial rise of fetal loss in both groups. In cases with no predisposing factors, the added fetal loss rate was 0.03%. previous abortions and bleeding during the current pregnancy are associated withthe most fetal losses after amniocentesis. In the absence of these, the added fetal loss rate (0.03%) is non-significant. Copyright (C) 2000 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 00:23:28