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Titolo:
Potential role for Ginkgo biloba extract in the treatment of glaucoma
Autore:
Ritch, R;
Indirizzi:
New York Eye & Ear Infirm, Dept Ophthalmol, Glaucoma Serv, New York, NY 10003 USA New York Eye & Ear Infirm New York NY USA 10003 v, New York, NY 10003 USA New York Med Coll, Valhalla, NY 10595 USA New York Med Coll Valhalla NY USA 10595 Med Coll, Valhalla, NY 10595 USA
Titolo Testata:
MEDICAL HYPOTHESES
fascicolo: 2, volume: 54, anno: 2000,
pagine: 221 - 235
SICI:
0306-9877(200002)54:2<221:PRFGBE>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLATELET-ACTIVATING-FACTOR; LOW-TENSION GLAUCOMA; OPEN-ANGLE GLAUCOMA; OPTIC-NERVE HEAD; CALCIUM-CHANNEL BLOCKERS; OCULAR BLOOD-FLOW; FREE-RADICAL SCAVENGERS; RETINAL GANGLION-CELLS; HUMAN ERYTHROCYTE-MEMBRANES; NORMAL-PRESSURE GLAUCOMA;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
271
Recensione:
Indirizzi per estratti:
Indirizzo: Ritch, R New York Eye & Ear Infirm, Dept Ophthalmol, Glaucoma Serv, 310 E 14th St, New York, NY 10003 USA New York Eye & Ear Infirm 310 E 14th St NewYork NY USA 10003 USA
Citazione:
R. Ritch, "Potential role for Ginkgo biloba extract in the treatment of glaucoma", MED HYPOTH, 54(2), 2000, pp. 221-235

Abstract

Glaucoma is becoming recognized as a condition for which not only elevatedintraocular pressure, but also non-pressure-dependent risk factors are responsible. New avenues of treatment into which investigations are being initiated include agents which could possibly improve blood flow to the eye andneuroprotective drugs. Only calcium channel blockers are presently available for such treatment in glaucoma, and these have not been widely adopted, in contrast to clinical trials involving a number of neuroprotectants in other neurologic disorders. Ginkgo biloba extract is freely available and hasseveral biological actions which combine to make it a potentially important agent in the treatment of glaucoma: improvement of central and peripheralblood flow, reduction of vasospasm, reduction of serum viscosity, antioxidant activity, platelet activating factor inhibitory activity, inhibition ofapoptosis, and inhibition of excitotoxicity. The effect of Ginkgo biloba extract as a potential antiglaucoma therapy deserves intensive scrutiny. (C)2000 Harcourt Publishers Ltd

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 11:41:38