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Titolo:
Racial differences in endothelin-1 at rest and in response to acute stressin adolescent males
Autore:
Treiber, FA; Jackson, RW; Davis, H; Pollock, JS; Kapuku, G; Mensah, GA; Pollock, DM;
Indirizzi:
Georgia Prevent Inst, Augusta, GA 30912 USA Georgia Prevent Inst Augusta GA USA 30912 ent Inst, Augusta, GA 30912 USA Med Coll Georgia, Dept Pediat, Vasc Biol Ctr, Augusta, GA 30912 USA Med Coll Georgia Augusta GA USA 30912 asc Biol Ctr, Augusta, GA 30912 USA Med Coll Georgia, Dept Psychiat, Augusta, GA 30912 USA Med Coll Georgia Augusta GA USA 30912 ept Psychiat, Augusta, GA 30912 USA Med Coll Georgia, Off Biostat, Augusta, GA 30912 USA Med Coll Georgia Augusta GA USA 30912 Off Biostat, Augusta, GA 30912 USA
Titolo Testata:
HYPERTENSION
fascicolo: 3, volume: 35, anno: 2000,
pagine: 722 - 725
SICI:
0194-911X(200003)35:3<722:RDIEAR>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLD PRESSOR TEST; ESSENTIAL-HYPERTENSION; PLASMA ENDOTHELIN; LABORATORY STRESSORS; BLOOD-PRESSURE; MENTAL STRESS; CHILDREN; BLACKS; GENDER;
Keywords:
endothelin; stress; blood pressure; race; young adults; blacks; hypertension, essential;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Treiber, FA Georgia Prevent Inst, Augusta, GA 30912 USA Georgia Prevent Inst Augusta GA USA 30912 gusta, GA 30912 USA
Citazione:
F.A. Treiber et al., "Racial differences in endothelin-1 at rest and in response to acute stressin adolescent males", HYPERTENSIO, 35(3), 2000, pp. 722-725

Abstract

Blacks exhibit greater vasoconstriction-mediated blood pressure (BP) increases in response to stress than do whites. Endothelin-1 (ET-1), a potent vasoconstrictive peptide, has been proposed as having a role in racial differences in stress reactivity, We evaluated the hemodynamic and plasma ET-1 levels of 41 (23 whites, 18 blacks, mean age 18.6 years) normotensive adolescent males at rest and in response to a video game challenge and forehead cold stimulation. Measurements were performed at catheter insertion and before and immediately after the 2 stressors, which were separated by 20-minute rest periods. Blacks exhibited higher absolute levels of diastolic blood pressure, total peripheral resistance index, or both in response to catheter insertion and to the video game challenge and during recovery from video game challenge and cold stimulation (P<0.05 for all). Blacks exhibited higherabsolute levels of ET-1 at every evaluation point (P<0.05 for all) and greater increases in ET-1 in response to both stressors (ps<0.05). These findings suggest that altered endothelial function may be involved in racial differences in hemodynamic reactivity to stress and possibly in the development of essential hypertension.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:16:10